Silencing of MEG3 inhibited ox‐LDL‐induced inflammation and apoptosis in macrophages via modulation of the MEG3/miR‐204/CDKN2A regulatory axis
Sign Up to like & getrecommendations! Published in 2019 at "Cell Biology International"
DOI: 10.1002/cbin.11105
Abstract: Atherosclerosis (AS) is one of the most common chronic inflammatory diseases and a major cause of morbidity and mortality. However, the underlying molecular mechanisms of the progression of AS are still largely unknown. Increasing evidence… read more here.
Keywords: meg3; cells treated; cdkn2a; mir 204 ... See more keywords
Coenzyme Q10 inhibits RANKL‐induced osteoclastogenesis by regulation of mitochondrial apoptosis and oxidative stress in RAW264.7 cells
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22778
Abstract: Coenzyme Q10 (CoQ10) has been reported to improve bone density and the number of trabeculae in postmenopausal osteoporosis, but the mechanism remains to be elucidated. We aimed to investigate the effects of CoQ10 on receptor… read more here.
Keywords: induced osteoclastogenesis; rankl induced; mitochondrial apoptosis; raw264 cells ... See more keywords
Amifostine inhibited the differentiation of RAW264.7 cells into osteoclasts by reducing the production of ROS under 2 Gy radiation
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29247
Abstract: Patients with malignant tumors receive radiotherapy, and radiation could harm the skeletal system, leading to radiation‐induced osteoporosis. A major cause of this phenomenon is the activation of osteoclasts by radiotherapy. In this study, we studied… read more here.
Keywords: cells osteoclasts; inhibited differentiation; ami; raw264 cells ... See more keywords
Metabolomic analysis reveals the influences of IC50 vitamin D3 on RAW264.7 cells based on 1 H NMR and UPLC-MS/MS.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.11882
Abstract: BACKGROUND As a lipid-soluble vitamin necessary for normal human physiology, vitamin D is mostly used in fortified foods, medicines, and adjuvant treatment of diseases. However, taken in high doses, vitamin D can be toxic. METHODS… read more here.
Keywords: nmr uplc; analysis reveals; ic50 vitamin; metabolomic analysis ... See more keywords
Inhibitory effect of sulphated polysaccharide porphyran (isolated from Porphyra yezoensis) on RANKL‐induced differentiation of RAW264.7 cells into osteoclasts
Sign Up to like & getrecommendations! Published in 2018 at "Phytotherapy Research"
DOI: 10.1002/ptr.5988
Abstract: Safe and efficient therapeutic agents for bone diseases are required in natural sources. We previously found that edible seaweed‐derived polysaccharide porphyran exhibited anti‐inflammatory effects through the down regulation of nuclear factor‐κB. The aim of this… read more here.
Keywords: rankl induced; porphyran; raw264 cells; polysaccharide porphyran ... See more keywords
Immune-modulation effect of Halocynthia aurantium tunic lipid on RAW264.7 cells
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DOI: 10.1007/s10068-021-01017-4
Abstract: The current study evaluated the immune-regulatory potential of lipid extract from Halocynthia aurantium tunic on macrophage cells. The results showed that H. aurantium lipid is composed of primarily SFA (68.32%), followed by MUFA and PUFA… read more here.
Keywords: aurantium; aurantium tunic; raw264 cells; aurantium lipid ... See more keywords
Isolation, purification and structural characterization of two pectin‐type polysaccharides from Coreopsis tinctoria Nutt. and their proliferation activities on RAW264.7 cells
Sign Up to like & getrecommendations! Published in 2021 at "Glycoconjugate Journal"
DOI: 10.1007/s10719-021-09982-y
Abstract: Coreopsis tinctoria Nutt . ( C.tinctoria ) is an annual herb of the Compositae family with many health benefits, such as clearing heat, antioxidant and anticancer activity. In this paper, two polysaccharides were isolated from… read more here.
Keywords: tinctoria nutt; proliferation activities; proliferation; ctap ... See more keywords
Gingipains promote RANKL-induced osteoclastogenesis through the enhancement of integrin β3 in RAW264.7 cells
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Histology"
DOI: 10.1007/s10735-020-09865-w
Abstract: As a crucial virulence factor of Porphyromonas gingivalis , gingipains play an important role in periodontal destruction. This study aimed to investigate the effect of gingipains on osteoclastogenesis. We used RAW264.7 cells as osteoclast precursors… read more here.
Keywords: osteoclastogenesis; integrin; rankl induced; factor ... See more keywords
Chikusetsusaponin V Inhibits LPS-Activated Inflammatory Responses via SIRT1/NF-κB Signaling Pathway in RAW264.7 Cells
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DOI: 10.1007/s10753-018-0858-8
Abstract: It is becoming increasingly accepted that macrophage activation play a crucial role in many diseases associated with chronic inflammation, such as metabolic disease, including atherosclerosis, obesity, and diabetes. Recent studies have indicated that the regulation… read more here.
Keywords: sirt1; sirt1 signaling; lps induced; csv ... See more keywords
MiR-199a-3p Restrains Foaming and Inflammation by Regulating RUNX1 in Macrophages
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DOI: 10.1007/s12033-022-00484-2
Abstract: MiR-199a-3p was reported decreased in serum of coronary heart disease patients and human atherosclerotic plaques. This study aims to investigate the roles of miR-199a-3p in atherosclerosis (AS). AS was induced in ApoE−/− mice via high… read more here.
Keywords: mir 199a; raw264 cells; ldl induced; runx1 ... See more keywords
Preparation of Phosphatidyl-panthenol by phospholipase D-mediated transphosphatidylation and its anti-inflammatory activity on macrophage-like RAW264.7 cells
Sign Up to like & getrecommendations! Published in 2020 at "Biocatalysis and agricultural biotechnology"
DOI: 10.1016/j.bcab.2020.101629
Abstract: Abstract Panthenol is known to be pro-vitamin B5 and show several functions such as wound-healing, anti-oxidative, and anti-inflammatory activities. In this study, panthenol was phosphatidylated via phospholipase D (PLD)-mediated transphosphatidylation and its anti-inflammatory effects were… read more here.
Keywords: anti inflammatory; panthenol; raw264 cells; mediated transphosphatidylation ... See more keywords