Chemical inducer of regucalcin attenuates lipopolysaccharide-induced inflammatory responses in pancreatic MIN6 β-cells and RAW264.7 macrophages.
Sign Up to like & getrecommendations! Published in 2021 at "FEBS open bio"
DOI: 10.1002/2211-5463.13321
Abstract: We previously isolated derrisfolin A, a novel rotenoid derivative, from the stems of Derris trifoliata Lour. (Leguminosae). Here, we report that derrisfolin A induces the expression of endogenous regucalcin (RGN) protein in both pancreatic MIN6… read more here.
Keywords: raw264 macrophages; lps induced; min6 cells; cells raw264 ... See more keywords
Lipid composition of membrane microdomains isolated detergent‐free from PUFA supplemented RAW264.7 macrophages
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26138
Abstract: Profound alterations in the lipid profile of raft and non‐raft plasma membrane microdomains were found when RAW264.7 macrophages were supplemented with polyunsaturated fatty acids (PUFAs) in physiologically relevant concentrations. For the first time lipids in… read more here.
Keywords: pufa; raw264 macrophages; raft; detergent free ... See more keywords
Immunomodulatory effects of xanthan gum in LPS-stimulated RAW 264.7 macrophages.
Sign Up to like & getrecommendations! Published in 2017 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2017.04.003
Abstract: In this study, we evaluated the immunomodulatory effects of xanthan gum (XG) in RAW264.7 macrophages and the underlying molecular mechanisms. We used scanning electron microscopy (SEM) to analyze the morphology of XG-treated RAW264.7 cells with… read more here.
Keywords: raw264 macrophages; lps stimulated; immunomodulatory effects; xanthan gum ... See more keywords
In vitro immunomodulatory effects of acidic exopolysaccharide produced by Lactobacillus planetarium JLAU103 on RAW264.7 macrophages.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2019.11.169
Abstract: Previous work from our research group has isolated and purified an acidic exopolysaccharide (named EPS103) from Lactobacillus plantarum JLAU103, which had strong in vitro antioxidant activity. In this study, we investigated the in vitro immunomodulatory… read more here.
Keywords: jlau103; raw264 macrophages; raw264; activity ... See more keywords
Nrf2 exerts mixed inflammation and glucose metabolism regulatory effects on murine RAW264.7 macrophages.
Sign Up to like & getrecommendations! Published in 2019 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2019.03.023
Abstract: Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is a transcription factor that mediates a broad range of cellular antioxidative, detoxification and anti-inflammatory effects. However, the precise mechanism by which Nrf2 regulates inflammation and metabolism in macrophages… read more here.
Keywords: raw264 macrophages; metabolism; inflammation; inflammation glucose ... See more keywords
Nitro-oleic acid, a ligand of CD36, reduces cholesterol accumulation by modulating oxidized-LDL uptake and cholesterol efflux in RAW264.7 macrophages
Sign Up to like & getrecommendations! Published in 2020 at "Redox Biology"
DOI: 10.1016/j.redox.2020.101591
Abstract: Macrophages play a pivotal role in the early stages of atherosclerosis development; they excessively accumulate cholesterol in the cytosol in response to modified Low Density Lipoprotein (mLDL). The mLDL are incorporated through scavenger receptors. CD36… read more here.
Keywords: reduces cholesterol; raw264 macrophages; nitro oleic; oleic acid ... See more keywords
PUFA-Derived N-Acylethanolamide Probes Identify Peroxiredoxins and Small GTPases as Molecular Targets in LPS-Stimulated RAW264.7 Macrophages
Sign Up to like & getrecommendations! Published in 2022 at "ACS Chemical Biology"
DOI: 10.1021/acschembio.1c00355
Abstract: We studied the mechanistic and biological origins of anti-inflammatory poly-unsaturated fatty acid-derived N-acylethanolamines using synthetic bifunctional chemical probes of docosahexaenoyl ethanolamide (DHEA) and arachidonoyl ethanolamide (AEA) in RAW264.7 macrophages stimulated with 1.0 μg mL–1 lipopolysaccharide.… read more here.
Keywords: molecular targets; dhea aea; microscopy; raw264 macrophages ... See more keywords
Identification and activation of TLR4-mediated signalling pathways by alginate-derived guluronate oligosaccharide in RAW264.7 macrophages
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-01868-0
Abstract: Alginate, a natural acidic polysaccharide extracted from marine brown seaweeds, is composed of different blocks of β-(1, 4)-D-mannuronate (M) and its C-5 epimer α-(1, 4)-L-guluronate (G). Alginate-derived guluronate oligosaccharide (GOS) readily activates macrophages. However, to… read more here.
Keywords: raw264 macrophages; raw264; guluronate oligosaccharide; alginate derived ... See more keywords
Extract of Pinus densiflora needles suppresses acute inflammation by regulating inflammatory mediators in RAW264.7 macrophages and mice
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutical Biology"
DOI: 10.1080/13880209.2022.2079679
Abstract: Abstract Context Pinus densiflora Siebold & Zucc. (Pinaceae) needle extracts ameliorate oxidative stress, but research into their anti-inflammatory effects is limited. Objective To investigate antioxidant and anti-inflammatory effects of a Pinus densiflora needles (PINE) ethanol… read more here.
Keywords: inflammatory mediators; anti inflammatory; pinus densiflora; raw264 macrophages ... See more keywords
Dendropanax morbifera Branch Water Extract Increases the Immunostimulatory Activity of RAW264.7 Macrophages and Primary Mouse Splenocytes.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of medicinal food"
DOI: 10.1089/jmf.2019.4424
Abstract: Polyacetylenes in the bark of Dendropanax morbifera trees have been reported to promote immune cell proliferation and to strengthen the innate immune system. The immunomodulatory potential of D. morbifera branch water extract (DBW) was evaluated… read more here.
Keywords: raw264 macrophages; morbifera; dbw; morbifera branch ... See more keywords
NOD2‐mediated HDAC6/NF‐κb signalling pathway regulates ferroptosis induced by extracellular histone H3 in acute liver failure
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.17582
Abstract: Acute liver failure (ALF) is life‐threatening and often associated with high mortality rates. The aim of the present study was to investigate whether extracellular histone H3 could induce ferroptosis in hepatic macrophages in ALF and… read more here.
Keywords: liver failure; histone; extracellular histone; acute liver ... See more keywords