Ginsenoside Rb2 suppresses the glutamate-mediated oxidative stress and neuronal cell death in HT22 cells
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Ginseng Research"
DOI: 10.1016/j.jgr.2018.12.002
Abstract: Background The objective of our study was to analyze the neuroprotective effects of ginsenoside derivatives Rb1, Rb2, Rc, Rd, Rg1, and Rg3 against glutamate-mediated neurotoxicity in HT22 hippocampal mouse neuron cells. Methods The neuroprotective effect… read more here.
Keywords: rb2; treatment; glutamate mediated; cell ... See more keywords
Ginsenoside Rb2 Alleviated Atherosclerosis by Inhibiting M1 Macrophages Polarization Induced by MicroRNA-216a
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DOI: 10.3389/fphar.2021.764130
Abstract: Introduction: Atherosclerosis is a chronic disease characterized by the inflammatory process and lipid depositions. We previously reported that microRNA-216a (miR-216a) can accelerate the progression of atherosclerosis by promoting the polarization of M1 pro-inflammatory phenotype. Ginsenoside… read more here.
Keywords: mir 216a; rb2; atherosclerosis; polarization ... See more keywords
Immunomodulatory Effect of Ginsenoside Rb2 Against Cyclophosphamide-Induced Immunosuppression in Mice
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.927087
Abstract: Ginsenoside Rb2 (Rb2), a fundamental saponin produced and isolated from ginseng (Panax ginseng C.A. Meyer), has a wide range of biological actions. The objective of this investigation was to see if ginsenoside Rb2 has any… read more here.
Keywords: induced immunosuppression; ginsenoside rb2; rb2; immunomodulatory effect ... See more keywords
Ginsenoside Rb2 Alleviates Hepatic Lipid Accumulation by Restoring Autophagy via Induction of Sirt1 and Activation of AMPK
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DOI: 10.3390/ijms18051063
Abstract: Although Panax ginseng is a famous traditional Chinese medicine and has been widely used to treat a variety of metabolic diseases including hyperglycemia, hyperlipidemia, and hepatosteatosis, the effective mediators and molecular mechanisms remain largely unknown.… read more here.
Keywords: hepatic lipid; sirt1; accumulation; rb2 ... See more keywords