RBBP4 is an epigenetic barrier for the induced transition of pluripotent stem cells into totipotent 2C-like cells.
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DOI: 10.1093/nar/gkad219
Abstract: Cellular totipotency is critical for whole-organism generation, yet how totipotency is established remains poorly illustrated. Abundant transposable elements (TEs) are activated in totipotent cells, which is critical for embryonic totipotency. Here, we show that the… read more here.
Keywords: totipotency; rbbp4; totipotent like; like cells ... See more keywords