RBBP6 interactome: RBBP6 isoform 3/DWNN and Nek6 interaction is critical for cell cycle regulation and may play a role in carcinogenesis
Sign Up to like & getrecommendations! Published in 2021 at "Informatics in Medicine Unlocked"
DOI: 10.1016/j.imu.2021.100522
Abstract: Abstract RBBP6 is a multidomain protein, with four splice variants translated into four functional isoforms. RBBP6 isoform 1 has been reported to interact with TP53 and pRb as well as with proteins that regulate transcriptional… read more here.
Keywords: rbbp6; cell cycle; dwnn; cycle regulation ... See more keywords
Expression Analysis of RbBP6 in human cancers: a Prospective biomarker.
Sign Up to like & getrecommendations! Published in 2019 at "Anti-Cancer Drugs"
DOI: 10.1097/cad.0000000000000809
Abstract: Retinoblastoma binding protein 6 (RBBP6) is a cancerrelated protein that has been implicated in the regulation of cell cycle and apoptosis. RBBP6 isoform 1 has been demonstrated to interact with two tumour suppressors, p53 and… read more here.
Keywords: expression; biomarker; rbbp6; domain ... See more keywords
Downregulation of RBBP6 variant 1 during arsenic trioxide-mediated cell cycle arrest and curcumin-induced apoptosis in MCF-7 breast cancer cells
Sign Up to like & getrecommendations! Published in 2019 at "Future Science OA"
DOI: 10.2144/fsoa-2019-0047
Abstract: Aim: To determine the expression patterns of the RBBP6 spliced variants during arsenic trioxide-mediated cell cycle arrest and curcumin-induced apoptosis in MCF-7 cells. Materials & methods: As2O3 and curcumin were used to study cytotoxicity, cell… read more here.
Keywords: cycle arrest; rbbp6; cell cycle; apoptosis ... See more keywords