Is RBD a risk factor for impulse control disorder in Parkinson's disease?
Sign Up to like & getrecommendations! Published in 2020 at "Annals of neurology"
DOI: 10.1002/ana.25798
Abstract: OBJECTIVE To assess the association between REM sleep behavior disorder (RBD) and other determinants and incident impulse control disorder behaviors (ICBs) in patients with early Parkinson's disease (PD) using longitudinal data from the Parkinson's Progression Markers… read more here.
Keywords: risk; impulse control; control disorder; rbd ... See more keywords
Preliminary Structural Data Revealed That the SARS‐CoV‐2 B.1.617 Variant's RBD Binds to ACE2 Receptor Stronger Than the Wild Type to Enhance the Infectivity
Sign Up to like & getrecommendations! Published in 2021 at "Chembiochem"
DOI: 10.1002/cbic.202100191
Abstract: The evolution of new SARS‐CoV‐2 variants around the globe has made the COVID‐19 pandemic more worrisome, further pressuring the health care system and immunity. Novel variations that are unique to the receptor‐binding motif (RBM) of… read more here.
Keywords: 617 variant; rbd; receptor; sars cov ... See more keywords
Differential avidity determination of IgG directed towards the receptor‐binding domain (RBD) of SARS‐CoV‐2 wild‐type and its variants in one assay: Rational tool for the assessment of protective immunity
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28006
Abstract: The avidity (binding strength) of IgG directed towards the receptor‐binding domain (RBD) of spike protein has been recognized as a central marker in severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) serology. It seems to be… read more here.
Keywords: rbd; igg directed; directed towards; avidity ... See more keywords
A vaccine delivery system promotes strong immune responses against SARS‐CoV‐2 variants
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28475
Abstract: Global coronavirus disease 2019 (COVID‐19) pandemics highlight the need of developing vaccines with universal and durable protection against emerging SARS‐CoV‐2 variants. Here we developed an extended‐release vaccine delivery system (GP‐diABZI‐RBD), consisting the original SARS‐CoV‐2 WA1… read more here.
Keywords: cov variants; system; diabzi rbd; rbd ... See more keywords
Receptor‐binding domain‐based SARS‐CoV‐2 vaccine adjuvanted with cyclic di‐adenosine monophosphate enhances humoral and cellular immunity in mice
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28584
Abstract: Novel adjuvants are highly desired to improve immune responses of SARS‐CoV‐2 vaccines. This work reports the potential of the stimulator of interferon genes (STING) agonist adjuvant, the cyclic di‐adenosine monophosphate (c‐di‐AMP), in a SARS‐CoV‐2 vaccine… read more here.
Keywords: rbd; amp; mice; sars cov ... See more keywords
Association between REM sleep behavior disorder and impulsive–compulsive behaviors in Parkinson’s disease: a systematic review and meta-analysis of observational studies
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neurology"
DOI: 10.1007/s00415-019-09588-3
Abstract: Background Both REM sleep behavior disorder (RBD) and impulsive–compulsive behaviors (ICBs) are well-recognized non-motor features in patients with Parkinson’s disease (PD). Studies have given contradictory results about the potential association between RBD and ICBs. Methods… read more here.
Keywords: behavior disorder; compulsive behaviors; rem sleep; rbd ... See more keywords
In silico study of some selective phytochemicals against a hypothetical SARS-CoV-2 spike RBD using molecular docking tools
Sign Up to like & getrecommendations! Published in 2021 at "Computers in Biology and Medicine"
DOI: 10.1016/j.compbiomed.2021.104818
Abstract: Background This world is currently witnessing a pandemic outbreak of 'COVID-19' caused by a positive-strand RNA virus 'SARS-CoV-2’. Millions have succumbed globally to the disease, and the numbers are increasing day by day. The viral… read more here.
Keywords: silico study; mutated spike; study selective; spike protein ... See more keywords
Specific epitopes form extensive hydrogen-bonding networks to ensure efficient antibody binding of SARS-CoV-2: Implications for advanced antibody design
Sign Up to like & getrecommendations! Published in 2021 at "Computational and Structural Biotechnology Journal"
DOI: 10.1016/j.csbj.2021.03.021
Abstract: Neutralizing antibody targeting to the SARS-CoV-2 could provide powerful therapies. A neutralizing antibody CC12.1 which was found in SARS-CoV-2 patient samples provides potential protection from disease. The aim of molecular dynamics simulations is to identify… read more here.
Keywords: antibody; binding sars; key epitopes; rbd ... See more keywords
Hypoxia/pH dual-responsive nitroimidazole-modified chitosan/rose bengal derivative nanoparticles for enhanced photodynamic anticancer therapy
Sign Up to like & getrecommendations! Published in 2020 at "Dyes and Pigments"
DOI: 10.1016/j.dyepig.2020.108395
Abstract: Abstract Most of the traditional photosensitizers (PSs) used in photodynamic therapy (PDT) have poor tumor targeting and phototoxic side effects. Drug delivery systems can be designed to be triggered to release payload PSs in response… read more here.
Keywords: hypoxia; modified chitosan; rbd; rose bengal ... See more keywords
Serological reactivity of inactivated SARS-CoV-2 vaccine based on an S-RBD neutralizing antibody assay
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Infectious Diseases"
DOI: 10.1016/j.ijid.2022.01.064
Abstract: Objectives This study aimed to explore the regularity of S-RBD domain antibody reactivity after immunization with inactivated SARS-CoV-2 vaccine and evaluate the immune response effect of this vaccine. Design or methods Venous blood samples were… read more here.
Keywords: sars cov; positive rate; antibody; vaccine ... See more keywords
Differences in clinical characteristics when REM sleep behavior disorder precedes or comes after the onset of Parkinson's disease
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the Neurological Sciences"
DOI: 10.1016/j.jns.2017.08.3247
Abstract: OBJECTIVE Rapid eye movement (REM) sleep behavior disorder (RBD) is important not only as a preclinical symptom of Parkinson's disease (PD), but also as an aggravating symptom of PD. However, it is not known whether… read more here.
Keywords: behavior disorder; rem sleep; rbd; sleep behavior ... See more keywords