Sphingoid base in pineapple glucosylceramide suppresses experimental allergy by binding leukocyte mono-immunoglobulin-like receptor 3.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.11610
Abstract: BACKGROUND Increase of patients suffering from Type I hypersensitivity, including hay fever and food allergy, is a serious public health issue around the world. Recent studies have focused on allergy prevention by food factors with… read more here.
Keywords: leukocyte mono; glccer; mono immunoglobulin; rbl 2h3 ... See more keywords
Anti-degranulation response of herbal formula in RBL-2H3 cells.
Sign Up to like & getrecommendations! Published in 2019 at "Micron"
DOI: 10.1016/j.micron.2019.102819
Abstract: Allergic diseases not only bring serious economic burden to the patients, but also consume a lot of substantial resources of social medical systems. Thus, the prevention and treatment of allergic diseases are imperative. In this… read more here.
Keywords: formula; herbal formula; anti degranulation; rbl 2h3 ... See more keywords
Trigonelline: An alkaloid with anti-degranulation properties.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular immunology"
DOI: 10.1016/j.molimm.2019.12.020
Abstract: Trigonelline, one of the alkaloids contained in coffee, is important not only as one of the constituents of aroma and flavor in coffee but also as a useful source of nutrition. Its anti-microbial, anti-carcinogenic, and… read more here.
Keywords: degranulation; trigonelline; anti degranulation; degranulation effect ... See more keywords
Palmitoylethanolamide counteracts substance P-induced mast cell activation in vitro by stimulating diacylglycerol lipase activity
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neuroinflammation"
DOI: 10.1186/s12974-019-1671-5
Abstract: BackgroundPalmitoylethanolamide (PEA) is a pleiotropic endogenous lipid mediator currently used as a “dietary food for special medical purposes” against neuropathic pain and neuro-inflammatory conditions. Several mechanisms underlie PEA actions, among which the “entourage” effect, consisting… read more here.
Keywords: pea; rbl 2h3; mast cell; activity ... See more keywords
The lectin ArtinM activates RBL-2H3 mast cells without inducing degranulation
Sign Up to like & getrecommendations! Published in 2020 at "PLoS ONE"
DOI: 10.1371/journal.pone.0230633
Abstract: Mast cells are connective tissue resident cells with morphological and functional characteristics that contribute to their role in allergic and inflammatory processes, host defense and maintenance of tissue homeostasis. Mast cell activation results in the… read more here.
Keywords: mast cells; mast; inducing degranulation; rbl 2h3 ... See more keywords
Streptococcal H2O2 inhibits IgE-triggered degranulation of RBL-2H3 mast cell/basophil cell line by inducing cell death
Sign Up to like & getrecommendations! Published in 2020 at "PLoS ONE"
DOI: 10.1371/journal.pone.0231101
Abstract: Mast cells and basophils are central players in allergic reactions triggered by immunoglobulin E (IgE). They have intracellular granules containing allergic mediators (e.g., histamine, serotonin, inflammatory cytokines, proteases and β-hexosaminidase), and stimulation by IgE-allergen complex… read more here.
Keywords: degranulation; streptococcal h2o2; mast; rbl 2h3 ... See more keywords
Luteolin suppresses 5-hydroxytryptamine elevation in stimulated RBL-2H3 cells and experimental colitis mice
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Biochemistry and Nutrition"
DOI: 10.3164/jcbn.20-192
Abstract: Increased 5-hydroxytryptamine may be associated with the development and progression of inflammatory bowel disease. In this study, we examined the suppressive effect of flavonoids on the increased intra- and extracellular 5-hydroxytryptamine levels in rat mast… read more here.
Keywords: hydroxytryptamine; rbl 2h3; 2h3 cells; luteolin ... See more keywords
Ultramicronized N-Palmitoylethanolamine Regulates Mast Cell-Astrocyte Crosstalk: A New Potential Mechanism Underlying the Inhibition of Morphine Tolerance
Sign Up to like & getrecommendations! Published in 2023 at "Biomolecules"
DOI: 10.3390/biom13020233
Abstract: Persistent pain can be managed with opioids, but their use is limited by the onset of tolerance. Ultramicronized N-palmitoylethanolamine (PEA) in vivo delays morphine tolerance with mechanisms that are still unclear. Since glial cells are… read more here.
Keywords: morphine tolerance; ultramicronized palmitoylethanolamine; tolerance; pea ... See more keywords
Effects of Apigenin on RBL-2H3, RAW264.7, and HaCaT Cells: Anti-Allergic, Anti-Inflammatory, and Skin-Protective Activities
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21134620
Abstract: Apigenin (4′,5,7-trihydroxyflavone, flavonoid) is a phenolic compound that is known to reduce the risk of chronic disease owing to its low toxicity. The first study on apigenin analyzed its effect on histamine release in the… read more here.
Keywords: hacat cells; expression; rbl 2h3; hacat ... See more keywords