RBM10: Harmful or helpful‐many factors to consider
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DOI: 10.1002/jcb.26644
Abstract: RBM10 is an RNA binding motif (RBM) protein expressed in most, if not all, human and animal cells. Interest in RBM10 is rapidly increasing and its clinical importance is highlighted by its identification as the… read more here.
Keywords: harmful helpful; helpful many; rbm10 harmful; rbm10 function ... See more keywords
Rbm10 regulates inflammation development via alternative splicing of Dnmt3b
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DOI: 10.1093/intimm/dxx067
Abstract: RNA-binding motif 10 (Rbm10) is an RNA-binding protein that regulates alternative splicing, but its role in inflammation is not well defined. Here, we show that Rbm10 controls appropriate splicing of DNA (cytosine-5)-methyltransferase 3b (Dnmt3b), a… read more here.
Keywords: inflammation development; dnmt3b; alternative splicing; rbm10 ... See more keywords
Integrated Bioinformatics Analysis and Validation of the Prognostic Value of RBM10 Expression in Hepatocellular Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Management and Research"
DOI: 10.2147/cmar.s349884
Abstract: Background RBM10ʹs function in hepatocellular carcinoma (HCC) has rarely been addressed. We intend to explore the prognostic significance and therapeutic meaning of RBM10 in HCC in this study. Methods Multiple common databases were integrated to… read more here.
Keywords: hepatocellular carcinoma; hcc; rbm10 expression; expression ... See more keywords
RBM10 Deficiency Is Associated With Increased Immune Activity in Lung Adenocarcinoma
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DOI: 10.3389/fonc.2021.677826
Abstract: Introduction RBM10 is one of the frequently mutated genes in lung adenocarcinoma (LUAD). Previous studies have confirmed that RBM10 could suppress the disease progression and cell proliferation in LUAD, but its loss-of-function mutations are more… read more here.
Keywords: cohort; rbm10 deficient; expression; rbm10 ... See more keywords
A TARP Syndrome Phenotype Is Associated with a Novel Splicing Variant in RBM10
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DOI: 10.3390/genes13112154
Abstract: TARP syndrome (Talipes equinovarus, Atrial septal defect, Robin sequence, and Persistence of the left superior vena cava) is a rare genetic condition, caused by developmental defects during embryogenesis. The phenotypic spectrum of TARP shows high… read more here.
Keywords: tarp syndrome; rbm10; tarp; phenotype associated ... See more keywords
NPTX1 inhibits pancreatic cancer cell proliferation and migration and enhances chemotherapy sensitivity by targeting RBM10
Sign Up to like & getrecommendations! Published in 2022 at "Oncology Letters"
DOI: 10.3892/ol.2022.13275
Abstract: Pancreatic cancer (PC), one of the deadliest diseases worldwide, has exhibited an increasing incidence rate in recent years. The present study aimed to explore the biological mechanism of PC. Therefore, the expression levels of neuronal… read more here.
Keywords: cell; pancreatic cancer; rbm10 nptx1; rbm10 ... See more keywords