Genetic screening of the RNA-binding protein RBM24 and its binding sites in the SOX2 3’ untranslated region in a cohort of 50 patients with micro-anophthalmia
Sign Up to like & getrecommendations! Published in 2025 at "Ophthalmic Genetics"
DOI: 10.1080/13816810.2025.2467334
Abstract: ABSTRACT Microphthalmia and anophthalmia (M/A) are rare congenital eye anomalies with a birth prevalence of up to 1 in 10,000 births. The etiology of M/A can involve environmental and/or genetic factors, with a genetic origin… read more here.
Keywords: untranslated region; protein rbm24; rbm24; binding protein ... See more keywords
Rbm24 regulates inner-ear-specific alternative splicing and is essential for maintaining auditory and motor coordination
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DOI: 10.1080/15476286.2020.1817265
Abstract: ABSTRACT Tissue-specific alternative splicing (AS) is emerging as one of the most exciting types of mechanisms associated with organ development and disease. In the auditory system, many hearing-related genes undergo AS, and errors in this… read more here.
Keywords: rbm24; inner ear; ear specific; motor coordination ... See more keywords
RBM24 regulates phenotypic switching of smooth muscle cell in vascular remodeling by stabilizing JAK2 mRNA.
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DOI: 10.1093/cvr/cvaf219
Abstract: AIMS Vascular remodeling plays a crucial role in the pathogenesis of vascular diseases. Our previous research highlighted the significance of RNA-binding protein 24 (RBM24) in the pathogenesis of dilated cardiomyopathy and the development of the… read more here.
Keywords: phenotypic switching; vascular remodeling; jak2 mrna; rbm24 ... See more keywords