RNA binding protein RBM46 regulates mitotic-to-meiotic transition in spermatogenesis
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DOI: 10.1126/sciadv.abq2945
Abstract: Meiosis entry during spermatogenesis requires reprogramming from mitotic to meiotic gene expression profiles. Transcriptional regulation has been extensively studied in meiosis entry, but gain of function for master transcription factors is insufficient to down-regulate mitotic… read more here.
Keywords: spermatogenesis; rna binding; binding protein; rbm46 ... See more keywords
The germ cell-specific RNA binding protein RBM46 is essential for spermatogonial differentiation in mice
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DOI: 10.1371/journal.pgen.1010416
Abstract: Control over gene expression is exerted, in multiple stages of spermatogenesis, at the post-transcriptional level by RNA binding proteins (RBPs). We identify here an essential role in mammalian spermatogenesis and male fertility for ‘RNA binding… read more here.
Keywords: binding protein; rna binding; rbm46; mice ... See more keywords