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   Articles with "rbm8a" as a keyword



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The glycolytic enzyme ALDOA and the exon junction complex protein RBM8A are regulators of ribosomal biogenesis

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recommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"

DOI: 10.3389/fcell.2022.954358

Abstract: Cellular growth is a fundamental process of life and must be precisely controlled in multicellular organisms. Growth is crucially controlled by the number of functional ribosomes available in cells. The production of new ribosomes depends… read more here.

Keywords: rbm8a; exon junction; growth; ribosomal biogenesis ... See more keywords
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Molecular Insights and Prognosis Associated With RBM8A in Glioblastoma

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recommendations! Published in 2022 at "Frontiers in Molecular Biosciences"

DOI: 10.3389/fmolb.2022.876603

Abstract: Background: Glioblastoma (GBM) is the most invasive brain tumors, and it is associated with high rates of recurrence and mortality. The purpose of this study was to investigate the expression of RBM8A in GBM and… read more here.

Keywords: rbm8a; glioblastoma; prognosis; expression ... See more keywords
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Mechanism and Molecular Network of RBM8A-Mediated Regulation of Oxaliplatin Resistance in Hepatocellular Carcinoma

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recommendations! Published in 2020 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2020.585452

Abstract: RNA-binding motif protein 8A (RBM8A) is abnormally overexpressed in hepatocellular carcinoma (HCC) and involved in the epithelial-mesenchymal transition (EMT). The EMT plays an important role in the development of drug resistance, suggesting that RBM8A may… read more here.

Keywords: rbm8a; hepatocellular carcinoma; regulation oxaliplatin; resistance ... See more keywords

Transcriptomic Analyses of Brains of RBM8A Conditional Knockout Mice at Different Developmental Stages Reveal Conserved Signaling Pathways Contributing to Neurodevelopmental Diseases

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recommendations! Published in 2023 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms24054600

Abstract: RNA-binding motif 8A (RBM8A) is a core component of the exon junction complex (EJC) that binds pre-mRNAs and regulates their splicing, transport, translation, and nonsense-mediated decay (NMD). Dysfunction in the core proteins has been linked… read more here.

Keywords: rbm8a; brain; knockout mice; mice ... See more keywords