Abstract DDT02-01: RBN-2397: A first-in-class PARP7 inhibitor targeting a newly discovered cancer vulnerability in stress-signaling pathways
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DOI: 10.1158/1538-7445.am2020-ddt02-01
Abstract: RBN-2397: A first-in-class PARP7 inhibitor targeting a newly discovered cancer vulnerability in stress-signaling pathways PARP7 is a monoPARP that catalyzes the transfer of single units of ADP-ribose onto substrates to change their function (MARylation). PARP7… read more here.
Keywords: inhibitor; parp7; rbn 2397; 2397 first ... See more keywords