microRNA‐binding proteins: specificity and function
Sign Up to like & getrecommendations! Published in 2017 at "Wiley Interdisciplinary Reviews: RNA"
DOI: 10.1002/wrna.1414
Abstract: microRNA (miRNA) and RNA‐binding proteins (RBPs) have been studied widely in post‐transcriptional gene regulation. Previous work has focused on defining how miRNA and RBPs modulate target mRNA decay and translation as well as investigating how… read more here.
Keywords: mirna; binding proteins; specificity function; rbps ... See more keywords
New sequencing methodologies reveal interplay between multiple RNA-binding proteins and their RNAs
Sign Up to like & getrecommendations! Published in 2020 at "Current Genetics"
DOI: 10.1007/s00294-020-01066-y
Abstract: It is now established that base-pairing regulatory RNAs are key players in post-transcriptional regulatory networks where they affect the translation and/or stability of their target RNAs. In many cases, the base-pairing between two RNAs is… read more here.
Keywords: rna; rna binding; rbps; new sequencing ... See more keywords
Artificial intelligence in neurodegenerative disease research: use of IBM Watson to identify additional RNA-binding proteins altered in amyotrophic lateral sclerosis
Sign Up to like & getrecommendations! Published in 2017 at "Acta Neuropathologica"
DOI: 10.1007/s00401-017-1785-8
Abstract: Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease with no effective treatments. Numerous RNA-binding proteins (RBPs) have been shown to be altered in ALS, with mutations in 11 RBPs causing familial forms of the… read more here.
Keywords: disease; watson; amyotrophic lateral; rbps ... See more keywords
The SARS-CoV-2 RNA interactome
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Cell"
DOI: 10.1016/j.molcel.2021.04.022
Abstract: SARS-CoV-2 is an RNA virus whose success as a pathogen relies on its abilities to repurpose host RNA-binding proteins (RBPs) and to evade antiviral RBPs. To uncover the SARS-CoV-2 RNA interactome, we here develop a… read more here.
Keywords: cov rna; rna interactome; host; rbps ... See more keywords
The characteristic landscape of lncRNAs classified by RBP-lncRNA interactions across 10 cancers.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular bioSystems"
DOI: 10.1039/c7mb00144d
Abstract: RNA-binding proteins (RBPs) are key regulators of gene expression. Some long non-coding RNAs (lncRNAs) affect gene expression by interacting with RBPs. However, whether this influences the biological characteristics of lncRNAs in diseases still remains unknown.… read more here.
Keywords: categories lncrnas; characteristic landscape; two categories; rbps ... See more keywords
Mutational landscape of RNA-binding proteins in human cancers
Sign Up to like & getrecommendations! Published in 2018 at "RNA Biology"
DOI: 10.1080/15476286.2017.1391436
Abstract: ABSTRACT RNA Binding Proteins (RBPs) are a class of post-transcriptional regulatory molecules which are increasingly documented to be dysfunctional in cancer genomes. However, our current understanding of these alterations is limited. Here, we delineate the… read more here.
Keywords: driver rbps; mutational landscape; binding proteins; rna binding ... See more keywords
Hydraulic Characterization of Implantable Rotary Blood Pumps
Sign Up to like & getrecommendations! Published in 2019 at "IEEE Transactions on Biomedical Engineering"
DOI: 10.1109/tbme.2018.2876840
Abstract: Objective: The hydraulic properties of implantable rotary blood pumps (RBPs) determine their interaction with the cardiovascular system. A systematic comparison in this regard has not yet been performed for different clinically used RBPs. The aim… read more here.
Keywords: blood pumps; four rbps; rbps; implantable rotary ... See more keywords
Establishment and validation of an RNA binding protein-associated prognostic model for ovarian cancer
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Ovarian Research"
DOI: 10.1186/s13048-021-00777-1
Abstract: Background Ovarian cancer (OC) is one of the most common gynecological malignant tumors worldwide, with high mortality and a poor prognosis. As the early symptoms of malignant ovarian tumors are not obvious, the cause of… read more here.
Keywords: rbps; rna binding; ovarian cancer; target genes ... See more keywords
Characterization of dengue virus 3’UTR RNA binding proteins in mosquitoes reveals that AeStaufen reduces subgenomic flaviviral RNA in saliva
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1010427
Abstract: Dengue viruses (DENV) are expanding global pathogens that are transmitted through the bite of mosquitoes, mostly Aedes aegypti. As RNA viruses, DENV rely on RNA-binding proteins (RBPs) to complete their life cycle. Alternatively, RBPs can… read more here.
Keywords: subgenomic flaviviral; rna; rbps; dengue virus ... See more keywords
Transcriptome Analyses Identify an RNA Binding Protein Related Prognostic Model for Clear Cell Renal Cell Carcinoma
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2020.617872
Abstract: RNA binding proteins (RBPs) play a key role in post-transcriptional gene regulation. They have been shown to be dysfunctional in a variety of cancers and are closely related to the occurrence and progression of cancers.… read more here.
Keywords: ccrcc; rna binding; model; rbps ... See more keywords
Identification of the Functions and Prognostic Values of RNA Binding Proteins in Bladder Cancer
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2021.574196
Abstract: Post-transcriptional regulation plays a leading role in gene regulation and RNA binding proteins (RBPs) are the most important posttranscriptional regulatory protein. RBPs had been found to be abnormally expressed in a variety of tumors and… read more here.
Keywords: bladder cancer; binding proteins; rna binding; rbps ... See more keywords