microRNA‐binding proteins: specificity and function
Sign Up to like & getrecommendations! Published in 2017 at "Wiley Interdisciplinary Reviews: RNA"
DOI: 10.1002/wrna.1414
Abstract: microRNA (miRNA) and RNA‐binding proteins (RBPs) have been studied widely in post‐transcriptional gene regulation. Previous work has focused on defining how miRNA and RBPs modulate target mRNA decay and translation as well as investigating how… read more here.
Keywords: mirna; binding proteins; specificity function; rbps ... See more keywords
New sequencing methodologies reveal interplay between multiple RNA-binding proteins and their RNAs
Sign Up to like & getrecommendations! Published in 2020 at "Current Genetics"
DOI: 10.1007/s00294-020-01066-y
Abstract: It is now established that base-pairing regulatory RNAs are key players in post-transcriptional regulatory networks where they affect the translation and/or stability of their target RNAs. In many cases, the base-pairing between two RNAs is… read more here.
Keywords: rna; rna binding; rbps; new sequencing ... See more keywords
Artificial intelligence in neurodegenerative disease research: use of IBM Watson to identify additional RNA-binding proteins altered in amyotrophic lateral sclerosis
Sign Up to like & getrecommendations! Published in 2017 at "Acta Neuropathologica"
DOI: 10.1007/s00401-017-1785-8
Abstract: Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease with no effective treatments. Numerous RNA-binding proteins (RBPs) have been shown to be altered in ALS, with mutations in 11 RBPs causing familial forms of the… read more here.
Keywords: disease; watson; amyotrophic lateral; rbps ... See more keywords
Regulation of Alternative Splicing of Lipid Metabolism Genes in Sepsis-Induced Liver Damage by RNA-Binding Proteins
Sign Up to like & getrecommendations! Published in 2024 at "Inflammation"
DOI: 10.1007/s10753-024-02017-2
Abstract: RNA binding proteins (RBPs) have the potential for transcriptional regulation in sepsis-induced liver injury, but precise functions remain unclear. Our aim is to conduct a genome-wide expression analysis of RBPs and illuminate changes in the… read more here.
Keywords: alternative splicing; rbps; sepsis induced; expression ... See more keywords
The SARS-CoV-2 RNA interactome
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Cell"
DOI: 10.1016/j.molcel.2021.04.022
Abstract: SARS-CoV-2 is an RNA virus whose success as a pathogen relies on its abilities to repurpose host RNA-binding proteins (RBPs) and to evade antiviral RBPs. To uncover the SARS-CoV-2 RNA interactome, we here develop a… read more here.
Keywords: cov rna; rna interactome; host; rbps ... See more keywords
Regulatory roles of RNA binding proteins in the Hippo pathway
Sign Up to like & getrecommendations! Published in 2025 at "Cell Death Discovery"
DOI: 10.1038/s41420-025-02316-z
Abstract: The Hippo pathway represents a highly conserved evolutionary pathway, dysfunction of which has been implicated in various diseases. RNA-binding proteins (RBPs) intricately modulate gene expression through interacting with non-coding RNAs or other proteins. To data,… read more here.
Keywords: hippo pathway; regulatory roles; binding proteins; rbps ... See more keywords
Nuclear and cytoplasmic specific RNA binding proteome enrichment and its changes upon ferroptosis induction
Sign Up to like & getrecommendations! Published in 2024 at "Nature Communications"
DOI: 10.1038/s41467-024-44987-9
Abstract: The reported assay shows a subcellular-specific RNA labeling method for efficient enrichment and deep profiling of nuclear and cytoplasmic RBPs, the authors apply this to investigate changes of subcellular-specific RBP-RNA interactions in ferroptosis. The key… read more here.
Keywords: specific rna; rna; nuclear cytoplasmic; rbps ... See more keywords
The characteristic landscape of lncRNAs classified by RBP-lncRNA interactions across 10 cancers.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular bioSystems"
DOI: 10.1039/c7mb00144d
Abstract: RNA-binding proteins (RBPs) are key regulators of gene expression. Some long non-coding RNAs (lncRNAs) affect gene expression by interacting with RBPs. However, whether this influences the biological characteristics of lncRNAs in diseases still remains unknown.… read more here.
Keywords: categories lncrnas; characteristic landscape; two categories; rbps ... See more keywords
Mutational landscape of RNA-binding proteins in human cancers
Sign Up to like & getrecommendations! Published in 2018 at "RNA Biology"
DOI: 10.1080/15476286.2017.1391436
Abstract: ABSTRACT RNA Binding Proteins (RBPs) are a class of post-transcriptional regulatory molecules which are increasingly documented to be dysfunctional in cancer genomes. However, our current understanding of these alterations is limited. Here, we delineate the… read more here.
Keywords: driver rbps; mutational landscape; binding proteins; rna binding ... See more keywords
Refining the pool of RNA-binding domains advances the classification and prediction of RNA-binding proteins
Sign Up to like & getrecommendations! Published in 2024 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkae536
Abstract: Key Points Comprehensive analysis of RNA-related protein domains and families enriched in RNA-binding proteins (RBPs) Pan-species prediction of new RBPs, and prediction and validation of new RNA-binding domains Online resource with complete dataset including high-confidence… read more here.
Keywords: binding domains; binding proteins; rna; rfam ids ... See more keywords
Hydraulic Characterization of Implantable Rotary Blood Pumps
Sign Up to like & getrecommendations! Published in 2019 at "IEEE Transactions on Biomedical Engineering"
DOI: 10.1109/tbme.2018.2876840
Abstract: Objective: The hydraulic properties of implantable rotary blood pumps (RBPs) determine their interaction with the cardiovascular system. A systematic comparison in this regard has not yet been performed for different clinically used RBPs. The aim… read more here.
Keywords: blood pumps; four rbps; rbps; implantable rotary ... See more keywords