Elbasvir/grazoprevir and sofosbuvir for hepatitis C virus genotype 3 infection with compensated cirrhosis: A randomized trial
Sign Up to like & getrecommendations! Published in 2018 at "Hepatology"
DOI: 10.1002/hep.29852
Abstract: Many direct‐acting antiviral regimens have reduced activity in people with hepatitis C virus (HCV) genotype (GT) 3 infection and cirrhosis. The C‐ISLE study assessed the efficacy and safety of elbasvir/grazoprevir (EBR/GZR) plus sofosbuvir (SOF) with… read more here.
Keywords: ebr gzr; rbv; treatment; cirrhosis ... See more keywords
Retreatment with sofosbuvir, ledipasvir, and add-on ribavirin for patients who failed daclatasvir and asunaprevir combination therapy
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Gastroenterology"
DOI: 10.1007/s00535-017-1328-z
Abstract: BackgroundThe optimal retreatment regimen for patients with hepatitis C virus (HCV) infection who failed interferon-free, direct-acting antiviral (DAA) therapy is undetermined. In this study, we aimed to evaluate the efficacy and safety of 12-week retreatment… read more here.
Keywords: add ribavirin; rbv; patients failed; therapy ... See more keywords
Autoantibodies to cytoplasmic rods and rings in patients with hepatitis C virus infection treated with direct-acting antivirals: The role of prior treatment with interferon plus ribavirin.
Sign Up to like & getrecommendations! Published in 2019 at "Gastroenterologia y hepatologia"
DOI: 10.1016/j.gastrohep.2018.08.005
Abstract: INTRODUCTION The cytoplasmic rods-rings (RR) pattern is found in hepatitis C (HCV) patients treated with interferon-ribavirin when studied with ANA-IIF. Ribavirin aggregates/induces antigenic changes in IMPDH-2, an enzyme necessary for ribavirin action. PATIENTS AND METHOD… read more here.
Keywords: rbv; treated direct; hcv; rods rings ... See more keywords
Edible Insects but Not Solanum Torvum Improved Body Composition and Iron Status in Protein and Iron Deficient Rats (P24-007-19).
Sign Up to like & getrecommendations! Published in 2019 at "Current developments in nutrition"
DOI: 10.1093/cdn/nzz044.p24-007-19
Abstract: Objectives Nutritious underutilized foods (NUFs) such as Solanum torvum (STO) and edible insects are potential sustainable dietary approaches to prevent malnutrition and improve food security. However, little is known about nutrient bioavailability from NUFs. This… read more here.
Keywords: sto; insects; rbv; body composition ... See more keywords
1600. An Optimal Respiratory Syncytial Virus (RSV) Treatment in Lung Transplant Recipients: Oral Ribavirin, Inhaled Ribavirin, or Conservative Approach
Sign Up to like & getrecommendations! Published in 2018 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofy210.1428
Abstract: Abstract Background Respiratory syncytial virus (RSV) is a common community acquired infection in lung transplant recipients (LTRs). The mortality in RSV-infected LTRs has been reported as 10–20% despite antiviral therapy; however, there is no consensus… read more here.
Keywords: rbv; oral rbv; infection; rsv ... See more keywords
Oral and Inhaled Ribavirin Treatment for Respiratory Syncytial Virus Infection in Lung Transplant Recipients
Sign Up to like & getrecommendations! Published in 2019 at "Transplantation"
DOI: 10.1097/tp.0000000000002985
Abstract: Background. Respiratory syncytial virus (RSV) infection in lung transplant recipients (LTRs) causes mortality rates of 10%–20% despite antiviral therapy. Ribavirin (RBV) has been used to treat RSV-infected LTRs with limited data. Methods. A retrospective study… read more here.
Keywords: infection lung; rbv; oral rbv; syncytial virus ... See more keywords
Treatment of chronic hepatitis C with direct‐acting antivirals in patients with β‐thalassaemia major and advanced liver disease
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DOI: 10.1111/bjh.14640
Abstract: Interferon‐based regimens for chronic hepatitis C (CHC) were often deferred in patients with β‐thalasaemia major (β‐TM) due to poor efficacy and tolerance. Current guidelines recommend direct‐acting antivirals (DAAs) for these patients. The aim of this… read more here.
Keywords: rbv; hepatitis; disease; advanced liver ... See more keywords
Shift in disparities in hepatitis C treatment from interferon to DAA era: A population‐based cohort study
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DOI: 10.1111/jvh.12684
Abstract: We evaluated the shift in the characteristics of people who received interferon‐based hepatitis C virus (HCV) treatments and those who received recently introduced direct‐acting antivirals (DAAs) in British Columbia (BC), Canada. The BC Hepatitis Testers… read more here.
Keywords: shift; rbv; treatment; hcv ... See more keywords
Loss to follow‐up: A significant barrier in the treatment cascade with direct‐acting therapies
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Viral Hepatitis"
DOI: 10.1111/jvh.13228
Abstract: Effectiveness of direct‐acting antiviral (DAA) therapies could be influenced by patient characteristics such as comorbid conditions, which could lead to premature treatment discontinuation and/or irregular medical follow‐ups. Here, we evaluate loss to follow‐up and treatment… read more here.
Keywords: rbv; follow significant; treatment; loss follow ... See more keywords
Health utilities using SF-6D scores in Japanese patients with chronic hepatitis C treated with sofosbuvir-based regimens in clinical trials
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DOI: 10.1186/s12955-017-0598-8
Abstract: BackgroundHealth utilities are preference-based measures for health states which are typically used in economic analyses to estimate quality-adjusted life years. Our aim is to report the standard SF-6D health utility scores in Japanese patients with… read more here.
Keywords: scores japanese; rbv; treatment; japanese patients ... See more keywords
Restriction of H1N1 influenza virus infection by selenium nanoparticles loaded with ribavirin via resisting caspase-3 apoptotic pathway
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s177658
Abstract: Introduction Ribavirin (RBV) is a broad-spectrum antiviral drug. Selenium nanoparticles (SeNPs) attract much attention in the biomedical field and are used as carriers of drugs in current research studies. In this study, SeNPs were decorated… read more here.
Keywords: caspase; rbv; infection; h1n1 influenza ... See more keywords