Ricobendazole nanocrystals obtained by media milling and spray drying: pharmacokinetic comparison with the micronized form of the drug.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2020.119501
Abstract: Helminthic infections are produced by different types of worms and affect millions of people worldwide. Benzimidazole compounds such as ricobendazole (RBZ) are widely used to treat helminthiasis. However, their low aqueous solubility leads to poor… read more here.
Keywords: spray drying; rbz ncs; drug; milling spray ... See more keywords
The sodium salt of the enantiomers of ricobendazole: Preparation, solubility and chiroptical properties
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Pharmaceutical and Biomedical Analysis"
DOI: 10.1016/j.jpba.2017.01.057
Abstract: HIGHLIGHTSThe Na salts of the enantiomers of RBZ were obtained by a two‐step process.In the first step RBZ was resolved on a semipreparative scale by HPLC on the Chiralpak IG CSP.In the second step the… read more here.
Keywords: enantiomers rbz; solubility; sodium salt; rbz ... See more keywords
Topical Triamcinolone Acetonide-Loaded Liposome Formulation Used as an Adjuvant to Intravitreal Ranibizumab Therapy for Neovascular Age-Related Macular Degeneration
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DOI: 10.3390/pharmaceutics13091491
Abstract: Novel strategies have been developed to reduce or avoid intravitreal injections (IVTs) of the antiangiogenic (ranibizumab (RBZ)) and anti-inflammatory (triamcinolone acetonide (TA)) agents used to treat vitreoretinal diseases. One of the strategies includes liposomes. This… read more here.
Keywords: therapy; topical triamcinolone; triamcinolone acetonide; triamcinolone ... See more keywords