Recombinant C1q variants modulate macrophage responses but do not activate the classical complement pathway.
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DOI: 10.1016/j.molimm.2019.10.008
Abstract: Complement protein C1q plays a dual role in a number of inflammatory diseases such as atherosclerosis. While in later stages classical complement pathway activation by C1q exacerbates disease progression, C1q also plays a beneficial role… read more here.
Keywords: rc1q; complement pathway; classical complement; c1q ... See more keywords