Adjuvant Therapy for Non-Clear Cell Renal Cell Carcinoma-The Ascent Continues.
Sign Up to like & getrecommendations! Published in 2024 at "JAMA network open"
DOI: 10.1001/jamanetworkopen.2024.25251
Abstract: Surgery is the preferred treatment for localized renal cell carcinoma (RCC). Although pursued with curative intent, approximately 50% of patients will experience disease recurrence. Pembrolizumab was approved as adjuvant treatment for patients at high risk… read more here.
Keywords: rcc; cell; cell carcinoma; clear cell ... See more keywords
Serum long non‐coding RNA LINC00887 as a potential biomarker for diagnosis of renal cell carcinoma
Sign Up to like & getrecommendations! Published in 2020 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12930
Abstract: The identification of non‐invasive biomarkers for the detection of renal cell carcinoma (RCC) in early‐stage patients may help improve disease outcome. Certain long non‐coding RNAs (lncRNAs) have been reported to be possible biomarkers for the… read more here.
Keywords: rcc; potential biomarker; cell; early stage ... See more keywords
miR‐30d‐5p suppresses proliferation and autophagy by targeting ATG5 in renal cell carcinoma
Sign Up to like & getrecommendations! Published in 2020 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13025
Abstract: Previous reports have shown that miR‐30d‐5p functions as a tumor suppressor in prostate cancer and gallbladder carcinoma, but its role in renal cell carcinoma (RCC) remains elusive. This study was designed to explore the functional… read more here.
Keywords: carcinoma; rcc; mir 30d; proliferation autophagy ... See more keywords
Inhibition of EZH2 exerts antitumorigenic effects in renal cell carcinoma via LATS1
Sign Up to like & getrecommendations! Published in 2023 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13579
Abstract: The most common type of kidney cancer in adults is renal cell carcinoma (RCC), which accounts for approximately 90% of cases. RCC is a variant disease with numerous subtypes; the most common subtype is clear… read more here.
Keywords: cell carcinoma; cell; renal cell; ezh2 ... See more keywords
Selenoprotein M stimulates the proliferative and metastatic capacities of renal cell carcinoma through activating the PI3K/AKT/mTOR pathway
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Medicine"
DOI: 10.1002/cam4.2403
Abstract: High‐throughput sequencing methods have facilitated the identification of novel selenoproteins, which exert a vital role in the development and progression of tumor diseases. Recently, Selenoprotein M (SELM) is upregulated in several types of cancer. However,… read more here.
Keywords: renal cell; selm; rcc; cell carcinoma ... See more keywords
Self-reported quality of life as a predictor of mortality in renal cell carcinoma.
Sign Up to like & getrecommendations! Published in 2021 at "Cancer"
DOI: 10.1002/cncr.33956
Abstract: BACKGROUND This study evaluated the utility of self-reported quality of life (QOL) metrics in predicting mortality among all-comers with renal cell carcinoma (RCC) and externally tested the findings in a registry of patients with small… read more here.
Keywords: rcc; mortality; qol metrics; quality life ... See more keywords
Ancillary studies in fine needle aspiration of the kidney
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Cytopathology"
DOI: 10.1002/cncy.22029
Abstract: An increasing number of renal cell carcinomas (RCCs) require ancillary studies for diagnosis. The majority of renal fine needle aspirates do not require ancillary studies. Among the most common useful stains are cytokeratin 7 (separating… read more here.
Keywords: ancillary studies; rcc; fine needle; studies fine ... See more keywords
Alternative splice variants of DCLK1 mark cancer stem cells, promote self‐renewal and drug‐resistance, and can be targeted to inhibit tumorigenesis in kidney cancer
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Cancer"
DOI: 10.1002/ijc.31400
Abstract: Renal cell carcinoma (RCC) is a common and devastating disease characterized by a hypoxic microenvironment, epithelial‐mesenchymal transition and potent resistance to therapy evidencing the presence of cancer stem cells (CSCs). Various CSC markers have been… read more here.
Keywords: rcc; self renewal; resistance; cancer ... See more keywords
How to improve initial diagnostic accuracy of kidney tumours in childhood?—A non‐invasive approach
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Cancer"
DOI: 10.1002/ijc.34870
Abstract: Non‐invasive differentiation of paediatric kidney tumours is particularly important in the SIOP‐RTSG protocols, which recommend pre‐operative chemotherapy without histological confirmation. The identification of clinical and tumour‐related parameters may enhance diagnostic accuracy. Age, metastases, and tumour… read more here.
Keywords: age; rcc; kidney tumours; diagnostic accuracy ... See more keywords
FSCN1 predicts survival and is regulated by a PI3K‐dependent mechanism in renal cell carcinoma
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26264
Abstract: While overexpression of FSCN1 is reported in several cancers, the prognostic significance of FSCN1 in renal cell carcinoma (RCC) and the molecular mechanisms involved remain largely unclear. We retrospectively enrolled 194 patients with non‐metastatic clear‐cell… read more here.
Keywords: cell carcinoma; renal cell; rcc; fscn1 ... See more keywords
MiR‐193a‐3p and miR‐224 mediate renal cell carcinoma progression by targeting alpha‐2,3‐sialyltransferase IV and the phosphatidylinositol 3 kinase/Akt pathway
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.22826
Abstract: Tumor metastasis is a major cause of cancer‐related death in renal cell carcinoma (RCC). MicroRNAs (miRNAs) have been widely known to modulate proliferation invasion, metastasis, and apoptosis of cancer cells. In this study, we aimed… read more here.
Keywords: 193a mir; mir 224; mir; rcc ... See more keywords