Serum long non‐coding RNA LINC00887 as a potential biomarker for diagnosis of renal cell carcinoma
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DOI: 10.1002/2211-5463.12930
Abstract: The identification of non‐invasive biomarkers for the detection of renal cell carcinoma (RCC) in early‐stage patients may help improve disease outcome. Certain long non‐coding RNAs (lncRNAs) have been reported to be possible biomarkers for the… read more here.
Keywords: rcc; potential biomarker; cell; early stage ... See more keywords
miR‐30d‐5p suppresses proliferation and autophagy by targeting ATG5 in renal cell carcinoma
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DOI: 10.1002/2211-5463.13025
Abstract: Previous reports have shown that miR‐30d‐5p functions as a tumor suppressor in prostate cancer and gallbladder carcinoma, but its role in renal cell carcinoma (RCC) remains elusive. This study was designed to explore the functional… read more here.
Keywords: carcinoma; rcc; mir 30d; proliferation autophagy ... See more keywords
Inhibition of EZH2 exerts antitumorigenic effects in renal cell carcinoma via LATS1
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DOI: 10.1002/2211-5463.13579
Abstract: The most common type of kidney cancer in adults is renal cell carcinoma (RCC), which accounts for approximately 90% of cases. RCC is a variant disease with numerous subtypes; the most common subtype is clear… read more here.
Keywords: cell carcinoma; cell; renal cell; ezh2 ... See more keywords
Selenoprotein M stimulates the proliferative and metastatic capacities of renal cell carcinoma through activating the PI3K/AKT/mTOR pathway
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DOI: 10.1002/cam4.2403
Abstract: High‐throughput sequencing methods have facilitated the identification of novel selenoproteins, which exert a vital role in the development and progression of tumor diseases. Recently, Selenoprotein M (SELM) is upregulated in several types of cancer. However,… read more here.
Keywords: renal cell; selm; rcc; cell carcinoma ... See more keywords
Self-reported quality of life as a predictor of mortality in renal cell carcinoma.
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DOI: 10.1002/cncr.33956
Abstract: BACKGROUND This study evaluated the utility of self-reported quality of life (QOL) metrics in predicting mortality among all-comers with renal cell carcinoma (RCC) and externally tested the findings in a registry of patients with small… read more here.
Keywords: rcc; mortality; qol metrics; quality life ... See more keywords
Ancillary studies in fine needle aspiration of the kidney
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DOI: 10.1002/cncy.22029
Abstract: An increasing number of renal cell carcinomas (RCCs) require ancillary studies for diagnosis. The majority of renal fine needle aspirates do not require ancillary studies. Among the most common useful stains are cytokeratin 7 (separating… read more here.
Keywords: ancillary studies; rcc; fine needle; studies fine ... See more keywords
Alternative splice variants of DCLK1 mark cancer stem cells, promote self‐renewal and drug‐resistance, and can be targeted to inhibit tumorigenesis in kidney cancer
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Cancer"
DOI: 10.1002/ijc.31400
Abstract: Renal cell carcinoma (RCC) is a common and devastating disease characterized by a hypoxic microenvironment, epithelial‐mesenchymal transition and potent resistance to therapy evidencing the presence of cancer stem cells (CSCs). Various CSC markers have been… read more here.
Keywords: rcc; self renewal; resistance; cancer ... See more keywords
FSCN1 predicts survival and is regulated by a PI3K‐dependent mechanism in renal cell carcinoma
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26264
Abstract: While overexpression of FSCN1 is reported in several cancers, the prognostic significance of FSCN1 in renal cell carcinoma (RCC) and the molecular mechanisms involved remain largely unclear. We retrospectively enrolled 194 patients with non‐metastatic clear‐cell… read more here.
Keywords: cell carcinoma; renal cell; rcc; fscn1 ... See more keywords
MiR‐193a‐3p and miR‐224 mediate renal cell carcinoma progression by targeting alpha‐2,3‐sialyltransferase IV and the phosphatidylinositol 3 kinase/Akt pathway
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DOI: 10.1002/mc.22826
Abstract: Tumor metastasis is a major cause of cancer‐related death in renal cell carcinoma (RCC). MicroRNAs (miRNAs) have been widely known to modulate proliferation invasion, metastasis, and apoptosis of cancer cells. In this study, we aimed… read more here.
Keywords: 193a mir; mir 224; mir; rcc ... See more keywords
Role of MR texture analysis in histological subtyping and grading of renal cell carcinoma: a preliminary study
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DOI: 10.1007/s00261-019-02122-z
Abstract: PurposeThe study evaluated the usefulness of magnetic resonance imaging (MRI) texture parameters in differentiating clear cell renal carcinoma (CC-RCC) from non-clear cell carcinoma (NC-RCC) and in the histological grading of CC-RCC.Materials and methodsAfter institutional ethical… read more here.
Keywords: grade; rcc; study; texture analysis ... See more keywords
Characterization of clear cell renal cell carcinoma and other renal tumors: evaluation of dual-energy CT using material-specific iodine and fat imaging
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DOI: 10.1007/s00330-019-06590-1
Abstract: Objective This study aimed to assess material-specific iodine and fat images for diagnosis of clear cell renal cell carcinoma (cc-RCC) compared to papillary RCC (p-RCC) and other renal masses. Materials and methods With IRB approval,… read more here.
Keywords: iodine concentration; material specific; rcc; cell ... See more keywords