Serum PD-1 levels measured by ELISA using Nivolumab increased in advanced RCC patients: novel approach to develop companion diagnostics for antibody therapy
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cancer Research and Clinical Oncology"
DOI: 10.1007/s00432-018-2806-2
Abstract: Antibody therapy targeting specific molecules has been successfully used to treat various diseases including RCC, but some patients do not respond to the therapy (Motzer et al. 2015). There is an urgent need to develop… read more here.
Keywords: antibody therapy; rcc patients; develop companion; antibody ... See more keywords
Comparison of two detection systems for circulating tumor cells among patients with renal cell carcinoma
Sign Up to like & getrecommendations! Published in 2018 at "International Urology and Nephrology"
DOI: 10.1007/s11255-018-1954-2
Abstract: Background/aimsDetection of circulating tumor cells (CTCs) in cancer patients has diagnostic and prognostic importance. However, the clinical implications of CTC detection in patients with renal cell carcinoma (RCC) are still unclear. In this study, we… read more here.
Keywords: detection; rcc patients; tumor cells; circulating tumor ... See more keywords
Gut Bacteria Composition Drives Primary Resistance to Cancer Immunotherapy in Renal Cell Carcinoma Patients.
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DOI: 10.1016/j.eururo.2020.04.044
Abstract: BACKGROUND The development of immune checkpoint blockade (ICB) has revolutionized the clinical outcome of renal cell carcinoma (RCC). Nevertheless, improvement of durability and prediction of responses remain unmet medical needs. While it has been recognized… read more here.
Keywords: renal cell; rcc patients; composition; cancer ... See more keywords
Role of leptin as a biomarker for early detection of renal cell carcinoma? No evidence from a systematic review and meta-analysis.
Sign Up to like & getrecommendations! Published in 2019 at "Medical hypotheses"
DOI: 10.1016/j.mehy.2019.109239
Abstract: Renal cell carcinoma (RCC) is the commonest from of renal neoplasm. Although surgery is a successful curative treatment for localized RCC, most patients are diagnosed with advanced or metastatic RCC, which has poor prognosis. RCC… read more here.
Keywords: rcc; rcc patients; leptin; biomarker early ... See more keywords
Editorial Comment from Dr Kadono to Timing and distribution of early renal cell carcinoma recurrences stratified by pathological nodal status in M0 patients at the time of nephrectomy
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Urology"
DOI: 10.1111/iju.14274
Abstract: The widespread use of cross-sectional imaging in the past two decades has increased the detection of incidental renal tumors. Furthermore, up to 30% of patients who underwent curative treatment for localized renal cell carcinoma (RCC)… read more here.
Keywords: renal cell; timing distribution; rcc patients; cell carcinoma ... See more keywords
Abstract 3973: Nivolumab-based ELISA revealed increased serum PD-1 levels in advanced RCC patients
Sign Up to like & getrecommendations! Published in 2019 at "Immunology"
DOI: 10.1158/1538-7445.am2019-3973
Abstract: Introduction: Antibody therapy has been successfully used for several caners, but the efficacy is still limited. To select patients that respond well to the therapy, development of companion diagnostics is essential. Although PD-L1 expression determined… read more here.
Keywords: rcc patients; nivolumab based; antibody; serum levels ... See more keywords
Tumor-Educated Platelets as a Promising Biomarker for Blood-Based Detection of Renal Cell Carcinoma
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DOI: 10.3389/fonc.2022.844520
Abstract: Purpose Tumor-educated platelets (TEPs) are a promising liquid biopsy in many cancers. However, their role in renal cell carcinoma (RCC) is unknown. Thus, this study explored the diagnostic value of TEPs in RCC patients. Methods… read more here.
Keywords: rcc patients; tumor; validation; tep model ... See more keywords
Prognostic value of glucose to lymphocyte ratio for patients with renal cell carcinoma undergoing laparoscopic nephrectomy: A multi-institutional, propensity score matching cohort study
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DOI: 10.3389/fsurg.2022.911411
Abstract: Background We evaluated the prognostic value of preoperative blood glucose to lymphocyte ratio (GLR) in renal cell carcinoma (RCC) patients who underwent laparoscopic nephrectomy through a multi-institutional clinical study. Methods A total of 420 patients… read more here.
Keywords: rcc patients; high glr; ratio; value ... See more keywords
The Medical Outcomes Distribution and the Interpretation of Clinical Data Based on C4.5 Algorithm for the RCC Patients in Taiwan
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DOI: 10.3390/app11062566
Abstract: The aim of our study is to explore the medical outcomes among patients in the respiratory care center (RCC) and related factors. A cross-sectional study was performed at a regional hospital in central Taiwan from… read more here.
Keywords: medical outcomes; interpretation clinical; rcc patients; distribution interpretation ... See more keywords