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   Articles with "rcc2" as a keyword



circRNA-0015004 act as a ceRNA to promote RCC2 expression in hepatocellular carcinoma

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recommendations! Published in 2024 at "Scientific Reports"

DOI: 10.1038/s41598-024-67819-8

Abstract: Although circular RNAs (circRNA) have been demonstrated to modulate tumor initiation and progression, their roles in the proliferation of hepatocellular carcinoma (HCC) are still poorly understood. Based on the analysis of GEO data (GSE12174), hsa-circRNA-0015004… read more here.

Keywords: rcc2; hcc; circ 0015004; hepatocellular carcinoma ... See more keywords

NudCL2 is required for cytokinesis by stabilizing RCC2 with Hsp90 at the midbody

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recommendations! Published in 2024 at "Protein & Cell"

DOI: 10.1093/procel/pwae025

Abstract: Abstract Cytokinesis is required for faithful division of cytoplasmic components and duplicated nuclei into two daughter cells. Midbody, a protein-dense organelle that forms at the intercellular bridge, is indispensable for successful cytokinesis. However, the regulatory… read more here.

Keywords: rcc2; midbody; cytokinesis; required cytokinesis ... See more keywords

RCC2 Promotes Esophageal Cancer Growth by Regulating Activity and Expression of the Sox2 Transcription Factor

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recommendations! Published in 2020 at "Molecular Cancer Research"

DOI: 10.1158/1541-7786.mcr-19-1152

Abstract: Regulator of chromosome condensation 2 (RCC2) is a protein located in the centrosome, which ensures that cell division proceeds properly. Previous reports show that RCC2 is overexpressed in some cancers and could play a key… read more here.

Keywords: expression; rcc2; growth; esophageal cancer ... See more keywords

RCC2 Interacts with Small GTPase RalA and Regulates Cell Proliferation and Motility in Gastric Cancer

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recommendations! Published in 2020 at "OncoTargets and therapy"

DOI: 10.2147/ott.s228914

Abstract: Background Regulator of chromosome condensation 2 (RCC2), also known as TD-60, is associated with various human malignant cancers. RCC2 has been shown to exhibit guanine exchange factor (GEF) activity and contribute to early mitosis. However,… read more here.

Keywords: rcc2; cell proliferation; cancer; gastric cancer ... See more keywords