Optimized dexamethasone immunosuppression enables Echinococcus multilocularis liver establishment after oral egg inoculation in a rat model.
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DOI: 10.1016/j.exppara.2017.02.003
Abstract: Comparable with immunocompetent humans, rats are considered highly resistant to Echinococcus multilocularis oncosphere invasion, both in nature and after experimental oral inoculation with eggs. Pharmacological immunosuppression with dexamethasone (DMX) was shown to abrogate the resistance… read more here.
Keywords: echinococcus multilocularis; inoculation; establishment; rcchan wist ... See more keywords