Blockade of T helper 17 cell function ameliorates recurrent Clostridioides difficile infection in mice.
Sign Up to like & getrecommendations! Published in 2021 at "Acta biochimica et biophysica Sinica"
DOI: 10.1093/abbs/gmab107
Abstract: Clostridioides difficile infection (CDI) is a common infection of the gastrointestinal tract. Typically, 20%-30% of CDI patients experience recurrent C. difficile infection (RCDI). Although the role of Th17 in infectious and inflammatory diseases including CDI… read more here.
Keywords: difficile infection; clostridioides difficile; infection; group ... See more keywords
Durability and Long-term Clinical Outcomes of Fecal Microbiota Transplant Treatment in Patients With Recurrent Clostridium difficile Infection
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Infectious Diseases"
DOI: 10.1093/cid/cix1097
Abstract: Background Fecal microbiota transplant (FMT) appears safe and effective for treatment of recurrent Clostridium difficile infection (RCDI). However, durability, long-term clinical outcomes, and patient satisfaction after FMT are not well described. Methods Eligible patients who… read more here.
Keywords: difficile infection; treatment; post fmt; rcdi ... See more keywords
Genome Wide Analysis Reveals Host Genetic Variants that Associate with Reduction in Clostridium difficile Infection Recurrence (rCDI) in Patients Treated with Bezlotoxumab
Sign Up to like & getrecommendations! Published in 2017 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofx163.941
Abstract: Abstract Background Bezlotoxumab (BEZ) and actoxumab (ACT) are monoclonal antibodies against C. difficile toxins B and A, respectively. Patients receiving a single infusion of BEZ alone or with ACT in the MODIFY I/II trials showed… read more here.
Keywords: merck inc; rcdi; hold stock; stock ... See more keywords
Fecal microbiota transplantation in children: current concepts.
Sign Up to like & getrecommendations! Published in 2019 at "Current Opinion in Pediatrics"
DOI: 10.1097/mop.0000000000000787
Abstract: PURPOSE OF REVIEW Administration of fecal material into the gastrointestinal tract, termed fecal microbiota transplantation (FMT), is increasingly recognized as an effective treatment option for recurrent Clostridium difficile infection (RCDI). The impact of FMT on… read more here.
Keywords: treatment option; fmt; rcdi; microbiota transplantation ... See more keywords
P300 The role of FMT in reducing hospital admissions and length of stay
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DOI: 10.1136/gutjnl-2020-bsgcampus.374
Abstract: Introduction Clostridium difficile infection (CDI) is the most common healthcare associated infection in the NHS with 12,275 cases reported in England in 2018/19. Recurrent Clostridium Difficile infection (rCDI) is an increasingly common problem; the recurrence… read more here.
Keywords: difficile infection; fmt; length stay; rcdi ... See more keywords
Health care resource utilization and costs of recurrent Clostridioides difficile infection in the elderly: a real-world claims analysis.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of managed care & specialty pharmacy"
DOI: 10.18553/jmcp.2021.20395
Abstract: BACKGROUND: Clostridioides difficile infection (CDI) affected an estimated 365,000 persons in the United States in 2017. Despite a nationally decreasing trend of CDI cases, the population incidence of recurrent CDI (rCDI) has not improved. Elderly… read more here.
Keywords: index; cdi; rcdi; episode ... See more keywords
Faecal microbiota transplantation in patients with Clostridium difficile and significant comorbidities as well as in patients with new indications: A case series
Sign Up to like & getrecommendations! Published in 2017 at "World Journal of Gastroenterology"
DOI: 10.3748/wjg.v23.i39.7174
Abstract: Fecal microbiota transplantation (FMT) is effective in recurrent Clostridium difficile infection (rCDI). Knowledge of the safety and efficacy of FMT treatment in immune deficient patients is scarce. FMT has been suggested as a potential method… read more here.
Keywords: clostridium difficile; microbiota transplantation; rcdi; new indications ... See more keywords