Rhodopsin signaling mediates light-induced photoreceptor cell death in rd10 mice through a transducin-independent mechanism.
Sign Up to like & getrecommendations! Published in 2019 at "Human molecular genetics"
DOI: 10.1093/hmg/ddz299
Abstract: Retinitis pigmentosa (RP) is a debilitating blinding disease affecting over 1.5 million people worldwide, but the mechanisms underlying this disease are not well understood. One of the common models used to study RP is the… read more here.
Keywords: rd10 mice; photoreceptor cell; cell death;
Trans-Sclera Electrical Stimulation Improves Retinal Function in a Mouse Model of Retinitis Pigmentosa
Sign Up to like & getrecommendations! Published in 2022 at "Life"
DOI: 10.3390/life12111917
Abstract: Retinitis pigmentosa (RP) is a photoreceptor-degenerating disease with no effective treatment. Trans-corneal electrical stimulation has neuroprotective effects in degenerating retinas, but repeated applications cause corneal injury. To avoid the risk of corneal damage, here we… read more here.
Keywords: rd10 mice; electrical stimulation; trans sclera; retinitis pigmentosa ... See more keywords