Loss of RDM1 enhances hepatocellular carcinoma progression via p53 and Ras/Raf/ERK pathways
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DOI: 10.1002/1878-0261.12593
Abstract: Hepatocellular carcinoma (HCC), with its ineffective therapeutic options and poor prognosis, represents a global threat. In the present study, we show that RAD52 motif 1 (RDM1), a key regulator of DNA double‐strand break repair and… read more here.
Keywords: hepatocellular carcinoma; loss rdm1; rdm1; p53 ... See more keywords
RDM1 plays an oncogenic role in human lung adenocarcinoma cells
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-30071-y
Abstract: RAD52 motif containing 1 (RDM1) is involved in DNA damage repair pathway and RDM1−/− cells increase sensitivity to cisplatin, a common chemotherapy drug. Lung cancer is the leading cause of cancer death worldwide. However, the… read more here.
Keywords: lung adenocarcinoma; human lung; rdm1; role ... See more keywords