Evaluating methylation of human ribosomal DNA at each CpG site reveals its utility for cancer detection using cell-free DNA
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DOI: 10.1093/bib/bbac278
Abstract: Ribosomal deoxyribonucleic acid (DNA) (rDNA) repeats are tandemly located on five acrocentric chromosomes with up to hundreds of copies in the human genome. DNA methylation, the most well-studied epigenetic mechanism, has been characterized for most… read more here.
Keywords: methylation; rdna methylation; dna; cancer ... See more keywords