Identification of curcumin as a novel natural inhibitor of rDNA transcription
Sign Up to like & getrecommendations! Published in 2020 at "Cell Cycle"
DOI: 10.1080/15384101.2020.1843817
Abstract: ABSTRACT Ribosomal DNA (rDNA) transcription drives cell growth and cell proliferation via the product ribosomal RNA (rRNA), the essential component of ribosome. Given the fundamental role of rRNA in ribosome biogenesis, rDNA transcription has emerged… read more here.
Keywords: rdna transcription; inhibitor rdna; rdna; curcumin ... See more keywords
Impaired function of rDNA transcription initiation machinery leads to derepression of ribosomal genes with insertions of R2 retrotransposon
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkab1276
Abstract: Abstract Eukaryotic genomes harbor hundreds of rRNA genes, many of which are transcriptionally silent. However, little is known about selective regulation of individual rDNA units. In Drosophila melanogaster, some rDNA repeats contain insertions of the… read more here.
Keywords: insertions retrotransposon; derepression; rdna transcription; rdna units ... See more keywords