The genomic structure of a human chromosome 22 nucleolar organizer region determined by TAR cloning
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-82565-x
Abstract: The rDNA clusters and flanking sequences on human chromosomes 13, 14, 15, 21 and 22 represent large gaps in the current genomic assembly. The organization and the degree of divergence of the human rDNA units… read more here.
Keywords: tar cloning; tar; rdna units; nucleolar organizer ... See more keywords
Impaired function of rDNA transcription initiation machinery leads to derepression of ribosomal genes with insertions of R2 retrotransposon
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkab1276
Abstract: Abstract Eukaryotic genomes harbor hundreds of rRNA genes, many of which are transcriptionally silent. However, little is known about selective regulation of individual rDNA units. In Drosophila melanogaster, some rDNA repeats contain insertions of the… read more here.
Keywords: insertions retrotransposon; derepression; rdna transcription; rdna units ... See more keywords