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Enamine-Mediated 1,3-Dipolar Cycloaddition Reaction of Curcumin Derivatives with Azides: Direct Access to 1,4,5-Trisubstituted 1,2,3-Triazoles

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Published in 2017 at "Synthesis"

DOI: 10.1055/s-0036-1588385

Abstract: An enamine-mediated [3+2] organocatalytic 1,3-dipolar cy­cloaddition reaction of curcumin derivatives with azides has been developed. This strategy could generate 1,4,5-trisubstituted 1,2,3-triazoles in high yields and regioselectivities under mild conditions. read more here.

Keywords: enamine mediated; trisubstituted triazoles; curcumin derivatives; derivatives azides ... See more keywords