Lewis-Base-Catalyzed Alkylation Reaction of 4-Hydroxycoumarins with Allenoates: Regioselective Synthesis of 2H-[3,2-c] Furocoumarins and 4-Hydroxycoumarin Vinyl Ether Derivatives
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DOI: 10.1002/ajoc.201600631
Abstract: A milder, more regioselective and practical approach to C3 or O-alkylation reaction of 4-hydroxycoumarins has been established. Both 2H-[3,2-c] furocoumarins and 4-hydroxycoumarin vinyl ether derivatives could be efficiently prepared by alkylating 4-hydroxycoumarins with electron-deficient allenoates… read more here.
Keywords: vinyl ether; furocoumarins hydroxycoumarin; reaction hydroxycoumarins; reaction ... See more keywords