Cyclic acyl amidines as unexpected C4-donors for fully substituted pyridine ring formation in the base mediated reaction with malononitrile
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DOI: 10.1016/j.tetlet.2019.06.038
Abstract: Abstract A new one-step, pseudo four-component approach for the synthesis of fully substituted pyridines via ring-opening of the cyclic acyl amidine of 3-amino-1 H -isoindol-1-one and its aza-analogues during the reaction with malononitrile in the… read more here.
Keywords: pyridine ring; cyclic acyl; reaction; reaction malononitrile ... See more keywords