Chromographic Analysis and Cytotoxic Effects of Chlorhexidine and Sodium Hypochlorite Reaction Mixtures
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DOI: 10.1016/j.joen.2017.04.025
Abstract: Introduction The literature reveals controversies regarding the formation of para‐chloroaniline (PCA) when chlorhexidine (CHX) is mixed with sodium hypochlorite (NaOCl). This study aimed to investigate the stability of PCA in the presence of NaOCl and… read more here.
Keywords: reaction mixtures; pca; cytotoxic effects; sodium hypochlorite ... See more keywords
Rapid optimisation of fragments and hits to lead compounds from screening of crude reaction mixtures
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DOI: 10.1038/s42004-020-00367-0
Abstract: Fragment based methods are now widely used to identify starting points in drug discovery and generation of tools for chemical biology. A significant challenge is optimization of these weak binding fragments to hit and lead… read more here.
Keywords: reaction mixtures; rapid optimisation; crude reaction; lead compounds ... See more keywords
Analytical and preparative separation and isolation of functionalized fullerenes by conventional HPLC stationary phases: method development and column screening
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DOI: 10.1039/d0ra02814b
Abstract: Isolation and purification of functionalized fullerenes from often complex reaction mixtures is challenging due to the hydrophobic nature and low solubility in regular organic solvents. We have developed an HPLC method that efficiently, employing regular… read more here.
Keywords: functionalized fullerenes; analytical preparative; reaction mixtures; separation ... See more keywords