Construction of novel bridged aromatic ring-fused oxazocine frameworks via an N-heterocyclic carbene-catalyzed azabenzoin reaction and radical-initiated cascade cyclization
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DOI: 10.1039/d1qo00483b
Abstract: Abstract: A novel and efficient method for the construction of 1,5-methanobenzo[f][1,3]oxazocin-6-one compounds from o-vinyl benzaldehydes and N-acylarylimines has been developed. The synthesis proceeded through the sequential NHC-catalyzed azabenzoin reaction and radical-initiated regiospecific intramolecular cascade cyclizations.… read more here.
Keywords: catalyzed azabenzoin; aromatic ring; reaction radical; bridged aromatic ... See more keywords