(4 + 3) Cycloaddition Reaction of Sulfonylphthalide with N,N'-Cyclic Azomethine Imines: Synthesis of Pyrimidinone-Fused Naphthoquinones.
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DOI: 10.1021/acs.orglett.3c00683
Abstract: A base-mediated [4 + 3] cycloaddition reaction of sulfonylphthalide with N,N'-cyclic azomethine imines to facilely synthesize novel pyrimidinone-fused naphthoquinones is described. The prepared compounds can be readily converted to isoquinoline-1,4-dione derivatives via alkaline methanolysis. Alternatively,… read more here.
Keywords: cyclic azomethine; reaction sulfonylphthalide; sulfonylphthalide cyclic; azomethine imines ... See more keywords