Characterizing Two Cytochrome P450s in Tiacumicin Biosynthesis Reveals Reaction Timing for Tailoring Modifications.
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DOI: 10.1021/acs.orglett.9b03100
Abstract: Functions of the tailoring enzymes for the biosynthesis of tiacumicin B (1) have been previously determined. However, the reaction timing remains elusive. Herein, we report the in vitro biochemical characterization of two P450 enzymes TiaP1… read more here.
Keywords: biosynthesis; reaction timing; cytochrome p450s; two cytochrome ... See more keywords