On-Resin Passerini Reaction toward C-Terminal Photocaged Peptides.
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DOI: 10.1021/acs.orglett.9b04182
Abstract: An on-resin, three-component Passerini reaction was developed to synthesize C-terminal photocaged peptides. Highly compatible with conventional Fmoc SPPS, this reaction produces peptides with a C-terminal o-amido-6-nitroveratryl (αANV) ester in one pot with conserved chirality. Under… read more here.
Keywords: reaction toward; photocaged peptides; terminal photocaged; passerini reaction ... See more keywords