Photocatalytic Defluorinative Three-Component Reaction of α-Trifluoromethyl Alkenes, Alkenes, and Sodium Sulfinates: Synthesis of Monofluorocyclopentenes.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c02202
Abstract: A photocatalytic three-component reaction of α-trifluoromethyl alkenes, electron-rich alkenes, and sodium sulfinates for the synthesis of gem-difluoroalkenes in a radical/polar crossover manner was developed. Due to the strong electron-withdrawing nature of the sulfonyl group, the… read more here.
Keywords: trifluoromethyl alkenes; sodium sulfinates; component reaction; three component ... See more keywords