Rearrangement Reactions leading to Optically Active α,α‐Disubstituted Primary Allylamines
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.201601446
Abstract: Synthetic routes to α,α-disubstituted allylamines have been examined. Racemic compounds were conveniently prepared by thermal Overman rearrangements of primary allyl alcohols with trisubstituted double bonds, but rearrangement of these substrates by the only commercially available… read more here.
Keywords: optically active; reactions leading; rearrangement reactions; active disubstituted ... See more keywords
Cascade reactions leading to the mechanism of action of vinaxanthone and xanthofulvin, natural products that drive nerve repair
Sign Up to like & getrecommendations! Published in 2018 at "Tetrahedron"
DOI: 10.1016/j.tet.2018.02.068
Abstract: Abstract The natural products vinaxanthone and xanthofulvin promote regeneration in animal models of spinal cord injury and corneal transplant. However, inhibition of the initially described biological target of these compounds, semaphorin 3A, does not fully… read more here.
Keywords: cascade reactions; natural products; vinaxanthone xanthofulvin; leading mechanism ... See more keywords