Asymmetric Inverse-Electron-Demand Diels–Alder Reactions of 2-Pyrones by Lewis Acid Catalysis
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DOI: 10.1055/a-1371-4391
Abstract: Diels–Alder reactions of 2-pyrones with alkenes can provide highly functionalized [2,2,2]-bicyclic lactones under mild reaction conditions. Synthetic utilizations of these reactions have been well demonstrated in natural-product synthesis. Although several catalytic asymmetric strategies have been… read more here.
Keywords: diels alder; acid catalysis; lewis acid; alder reactions ... See more keywords
Reactions of 4-Pyrones with Azomethine Ylides as a Chemoselective Method for the Construction of Multisubstituted Pyrano[2,3-c]pyrrolidines
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DOI: 10.1055/s-0040-1706032
Abstract: 4-Pyrones bearing electron-donating and electron-withdrawing groups react with nonstabilized azomethine ylides to form pyrano[2,3-c]pyrrolidines in moderate to good yields. The reaction proceeds chemoselectively as a 1,3-dipolar cycloaddition of the azomethine ylide at the carbon–carbon double… read more here.
Keywords: pyrano pyrrolidines; azomethine ylides; pyrones azomethine; ylides chemo ... See more keywords