Articles with "reactive astrogliosis" as a keyword



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Erythropoietin protects the subventricular zone and inhibits reactive astrogliosis in kaolin-induced hydrocephalic rats

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Published in 2019 at "Child's Nervous System"

DOI: 10.1007/s00381-019-04063-w

Abstract: PurposeTo elucidate the potential role of erythropoietin (EPO) as a neuroprotective agent against reactive astrogliosis and reducing the thinning rate of subventricular zone (SVZ) in kaolin-induced hydrocephalic rats.MethodThirty-six ten-week-old Sprague-Dawley rats were used in this… read more here.

Keywords: hydrocephalic rats; subventricular zone; reactive astrogliosis; group ... See more keywords
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CDK5 inhibitors prevent astroglial apoptosis and reactive astrogliosis by regulating PKA and DRP1 phosphorylations in the rat hippocampus

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Published in 2017 at "Neuroscience Research"

DOI: 10.1016/j.neures.2017.01.006

Abstract: Status epilepticus (SE) results in the unique pattern of dynamin-related protein 1 (DRP1)-mediated mitochondrial dynamics, which is associated with astroglial apoptosis and reactive astrogliosis in the regional-specific pattern representing the differential astroglial properties. However, less… read more here.

Keywords: cdk5 inhibitors; reactive astrogliosis; astroglial apoptosis;
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The differential roles of PEA15 phosphorylations in reactive astrogliosis and astroglial apoptosis following status epilepticus

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Published in 2018 at "Neuroscience Research"

DOI: 10.1016/j.neures.2018.02.003

Abstract: Up to this day, the roles of PEA15 expression and its phosphorylation in seizure-related events have not been still unclear. In the present study, we found that PEA15 was distinctly phosphorylated in reactive astrocytes and… read more here.

Keywords: roles pea15; phosphorylation; astroglial apoptosis; reactive astrogliosis ... See more keywords
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Reactive astrogliosis: A friend or foe in the pathogenesis of Alzheimer's disease.

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Published in 2021 at "Journal of neurochemistry"

DOI: 10.1111/jnc.15565

Abstract: Astrocytes are highly efficient homeostatic glial cells playing a crucial role in the optimal brain functioning and homeostasis. Astrocytes respond to changes in brain homoeostasis following central nervous system (CNS) injury/diseased state by a specific… read more here.

Keywords: brain; reactive astrogliosis; astrogliosis friend; astrogliosis ... See more keywords
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Acupuncture at ST36 Exerts Neuroprotective Effects via Inhibition of Reactive Astrogliosis in Infantile Rats with Hydrocephalus

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Published in 2018 at "Acupuncture in Medicine"

DOI: 10.1136/acupmed-2017-011515

Abstract: Background Acupuncture has been associated with improved cerebral circulation, analgesia, neuromodulatory function and neurogenesis. In particular, acupuncture at ST36 has been widely used in several central nervous system (CNS) disorders, including neurodegenerative diseases. However, its… read more here.

Keywords: astrogliosis infantile; acupuncture st36; reactive astrogliosis; acupuncture ... See more keywords
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Reactive Astrogliosis: Implications in Spinal Cord Injury Progression and Therapy

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Published in 2020 at "Oxidative Medicine and Cellular Longevity"

DOI: 10.1155/2020/9494352

Abstract: Astrocytes are the most populous glial cells in the central nervous system (CNS). They are essential to CNS physiology and play important roles in the maintenance of homeostasis, development of synaptic plasticity, and neuroprotection. Nevertheless,… read more here.

Keywords: astrogliosis implications; reactive astrogliosis; astrogliosis; cord injury ... See more keywords
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Deep Learning–Based Segmentation of Morphologically Distinct Rat Hippocampal Reactive Astrocytes After Trimethyltin Exposure

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Published in 2022 at "Toxicologic Pathology"

DOI: 10.1177/01926233221124497

Abstract: As regulators of homeostasis, astrocytes undergo morphological changes after injury to limit the insult in central nervous system (CNS). Trimethyltin (TMT) is a known neurotoxicant that induces reactive astrogliosis in rat CNS. To evaluate the… read more here.

Keywords: rat; learning; reactive astrogliosis; based segmentation ... See more keywords
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Crystallin Alpha-B Overexpression as a Possible Marker of Reactive Astrogliosis in Human Cerebral Contusions

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Published in 2022 at "Frontiers in Cellular Neuroscience"

DOI: 10.3389/fncel.2022.838551

Abstract: The pathophysiology of traumatic brain injury (TBI) has not yet been fully elucidated. Crystallin alpha-B (CRYAB) is a molecular chaperone that apparently tries to stabilize the rapid thickening of the intermediate filaments of glial fibrillary… read more here.

Keywords: cryab; overexpression; expression; reactive astrogliosis ... See more keywords
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Corrigendum: Reactive astrogliosis in the era of single-cell transcriptomics

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Published in 2023 at "Frontiers in Cellular Neuroscience"

DOI: 10.3389/fncel.2023.1212975

Abstract: [This corrects the article DOI: 10.3389/fncel.2023.1173200.]. read more here.

Keywords: cell transcriptomics; reactive astrogliosis; corrigendum reactive; single cell ... See more keywords
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Imaging of Reactive Astrogliosis by Positron Emission Tomography

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Published in 2022 at "Frontiers in Neuroscience"

DOI: 10.3389/fnins.2022.807435

Abstract: Many neurodegenerative diseases are neuropathologically characterized by neuronal loss, gliosis, and the deposition of misfolded proteins such as β-amyloid (Aβ) plaques and tau tangles in Alzheimer’s disease (AD). In postmortem AD brains, reactive astrocytes and… read more here.

Keywords: reactive astrogliosis; positron emission; emission tomography; imaging reactive ... See more keywords