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Published in 2017 at "Clinical Cancer Research"
DOI: 10.1158/1078-0432.ccr-16-1692
Abstract: Purpose: Infusion of highly heterogeneous populations of autologous tumor-infiltrating lymphocytes (TIL) can result in tumor regression of exceptional duration. Initial tumor regression has been associated with persistence of tumor-specific TILs 1 month after infusion, but…
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Keywords:
tumor;
cd8;
cd8 cells;
reactive cd8 ... See more keywords
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Published in 2019 at "Genome Biology"
DOI: 10.1186/s13059-019-1921-y
Abstract: Tumor-reactive CD8+ tumor-infiltrating lymphocytes (TILs) represent a subtype of T cells that can recognize and destroy tumor specifically. Understanding the regulatory mechanism of tumor-reactive CD8+ T cells has important therapeutic implications. Yet the DNA methylation…
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Keywords:
methylation;
cd8;
cd8 cells;
reactive cd8 ... See more keywords