Hydrazide-based reactive matrices for the sensitive detection of aldehydes and ketones by MALDI mass spectrometry imaging.
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DOI: 10.1039/d4cc02475c
Abstract: A one-step, on-tissue chemical derivatisation method for MALDI mass spectrometry imaging was found to improve the detectability of aldehydes and ketones by charge-tagging. The developed reactive matrices, containing a UV-chromophore, ionisable moiety and hydrazide group,… read more here.
Keywords: mass spectrometry; spectrometry imaging; reactive matrices; aldehydes ketones ... See more keywords