Reactive Oxygen Species–Activatable Liposomes Regulating Hypoxic Tumor Microenvironment for Synergistic Photo/Chemodynamic Therapies
Sign Up to like & getrecommendations! Published in 2019 at "Advanced Functional Materials"
DOI: 10.1002/adfm.201905013
Abstract: Tumors have adapted various cellular antidotes and microenvironmental conditions to subsist against photodynamic therapy (PDT) and chemodynamic therapy (CDT). Here, the development of reactive oxygen species (ROS)‐activatable liposomes (RALP) for therapeutic enhancement by simultaneously addressing… read more here.
Keywords: tumor; tumor microenvironment; activatable liposomes; oxygen species ... See more keywords
Near‐Infrared Chemiluminescent Reporters for In Vivo Imaging of Reactive Oxygen and Nitrogen Species in Kidneys
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DOI: 10.1002/adfm.202003628
Abstract: Despite the superior sensitivity of chemiluminescence over fluorescence, most chemiluminescence reporters only emit visible light, and have low water solubility, making them poorly equipped for in vivo imaging applications. Herein two near‐infrared (NIR) chemiluminescent reporters… read more here.
Keywords: reactive oxygen; imaging reactive; near infrared; vivo imaging ... See more keywords
Nanoclay Mediated Self‐Promoted Reactive Oxygen Species Releasing Enables Efficient Antimicrobial
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DOI: 10.1002/adfm.202407875
Abstract: Reactive oxygen species (ROS) releasing materials are increasingly used in nanomedicines due to their effectiveness against a broad spectrum of microbes. However, most ROS‐releasing materials rely on external stimuli such as photoirradiation, either through photodynamic… read more here.
Keywords: self promoted; oxygen; nanoclay mediated; oxygen species ... See more keywords
Triphenylamine‐Substituted Nile Red Derivatives with Efficient Reactive Oxygen Species Generation for Robust and Broad‐Spectrum Antimicrobial Photodynamic Therapy and Abscess Wound Healing
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202421072
Abstract: Infections caused by drug‐resistant bacteria represent a major contributor to high mortality rates, underscoring the urgent need for effective non‐antibiotic drugs and alternative therapies. Antimicrobial photodynamic therapy (aPDT) emerges as an innovative treatment due to… read more here.
Keywords: red derivatives; antimicrobial photodynamic; wound healing; nile red ... See more keywords
In Situ Reactive Oxygen Species‐Generating Semiconductor Nanopore for Real Time Peptide Oxidation Analysis
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DOI: 10.1002/adfm.202527203
Abstract: Photo‐induced damage impairs protein activity and leads to functional deterioration in organisms and tissues. In situ studies of peptide motifs oxidation are pivotal for elucidating molecular mechanisms of photodamage and identifying therapeutic targets. Although nanopores… read more here.
Keywords: oxygen species; oxidation; real time; reactive oxygen ... See more keywords
A Smart Hydrogel Dressing Balances Reactive Oxygen Species Levels for Effective Treatment of Bacteria‐Infected Atopic Dermatitis
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202501142
Abstract: Bacteria‐infected atopic dermatitis (AD) is an infectious inflammatory skin disease that profoundly disrupts patients' daily lives. As a viable alternative to antibiotic therapy, reactive oxygen species (ROS) treatment has emerged, effectively eradicating bacteria without the… read more here.
Keywords: hydrogel dressing; hydrogel; reactive oxygen; infected atopic ... See more keywords
Toxic Reactive Oxygen Species Enhanced Synergistic Combination Therapy by Self-Assembled Metal-Phenolic Network Nanoparticles.
Sign Up to like & getrecommendations! Published in 2018 at "Advanced materials"
DOI: 10.1002/adma.201704877
Abstract: Engineering functional nanomaterials with high therapeutic efficacy and minimum side effects has increasingly become a promising strategy for cancer treatment. Herein, a reactive oxygen species (ROS) enhanced combination chemotherapy platform is designed via a biocompatible… read more here.
Keywords: reactive oxygen; combination; oxygen species; metal ... See more keywords
Tumor Microenvironment-activated Reactive Oxygen Species Amplifier for Enzymatic Cascade Cancer Starvation/Chemodynamic /Immunotherapy.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced materials"
DOI: 10.1002/adma.202106010
Abstract: At present, some progresses have been made in the field of cancer theranostics based on nanocatalysts (NCs), but achieving the precisive theranostics in response to specific tumor microenvironment (TME) remains a major challenge. Herein, we… read more here.
Keywords: reactive oxygen; immunotherapy; starvation chemodynamic; cancer ... See more keywords
Sensitive Activatable Nanoprobes for Real‐Time Ratiometric Magnetic Resonance Imaging of Reactive Oxygen Species and Ameliorating Inflammation In Vivo
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DOI: 10.1002/adma.202109004
Abstract: Imaging‐guided real‐time monitoring of the treatment process of inflammatory diseases is important for the timely adjustment of treatment planning to lower unnecessary side effects and improve treatment outcomes. However, it is difficult to reflect the… read more here.
Keywords: magnetic resonance; reactive oxygen; inflammation; inflammation vivo ... See more keywords
Flexible Modulation of Cellular Activities with Cationic Photosensitizers: Insights of Alkyl Chain Length on Reactive Oxygen Species Antimicrobial Mechanisms.
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DOI: 10.1002/adma.202302943
Abstract: Cationic photosensitizers have good binding ability with negatively charged bacteria and fungi, exhibiting broad potential for use in antimicrobial photodynamic therapy (aPDT). However, cationic photosensitizers often display unsatisfactory transkingdom selectivity between mammalian cells and pathogens,… read more here.
Keywords: reactive oxygen; cellular activities; cationic photosensitizers; oxygen species ... See more keywords
Reactive Oxygen Species Resistive Redox Mediator in Lithium–Oxygen Batteries
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DOI: 10.1002/adma.202415805
Abstract: The utilization of redox mediators (RMs) in lithium–oxygen batteries (LOBs) has underscored their utility in high overpotential during the charging process. Among the currently known RMs, it is exceptionally challenging to identify those with a… read more here.
Keywords: oxygen; lithium oxygen; species resistive; oxygen species ... See more keywords