Smart supramolecular vesicles based on glutathione-reactive pillar[6]arene and acid-labile prodrug: Dual drug loading and sequential release
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DOI: 10.1016/j.cclet.2021.07.024
Abstract: Abstract Glutathione thiol-reactive pillar[6]arene (TWP6) is designed and synthesized as the first example of reducing agent-reactive host molecule. TWP6 shows high affinity binding towards suitable anti-tumor drugs and guests. Doxorubicin-based acid-labile prodrugs and TWP6 are… read more here.
Keywords: reactive pillar; sequential release; pillar arene; acid labile ... See more keywords