Biochemical characterization of the catecholaldehyde reactivity of l-carnosine and its therapeutic potential in human myocardium
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DOI: 10.1007/s00726-018-2647-y
Abstract: Oxidative deamination of norepinephrine (NE) and dopamine (DA) by monoamine oxidase (MAO) generates the catecholaldehydes 3,4-dihydroxyphenylglycolaldehyde (DOPEGAL) and 3,4-dihydroxyphenylacetaldehyde (DOPAL), respectively, and H2O2. Catecholaldehydes are highly reactive electrophiles that have been implicated as causal factors… read more here.
Keywords: reactivity carnosine; catecholaldehyde; myocardium; reactivity ... See more keywords