Cancer cell targeting driven by selective polyamine reactivity with glycine propargyl esters.
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DOI: 10.1039/c7cc01934c
Abstract: Rapidly growing cancer cells have increased levels of intracellular polyamines compared to normal, healthy tissues. Based on the selective reactivity of glycine propargyl esters, probes were synthesized that show evidence for selective polyamine reactivity, which… read more here.
Keywords: reactivity glycine; glycine propargyl; reactivity; propargyl esters ... See more keywords