Diverse Redoxome Reactivity Profiles of Carbon Nucleophiles.
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DOI: 10.1021/jacs.7b01791
Abstract: Targeted covalent inhibitors have emerged as a powerful approach in the drug discovery pipeline. Key to this process is the identification of signaling pathways (or receptors) specific to (or overexpressed in) disease cells. In this… read more here.
Keywords: reactivity profiles; ligand discovery; covalent;