Riluzole attenuates the efficacy of glutamatergic transmission by interfering with the size of the readily releasable neurotransmitter pool
Sign Up to like & getrecommendations! Published in 2018 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2018.09.021
Abstract: ABSTRACT Riluzole is a potent neuroprotective agent which primarily inhibits excitatory neurotransmission interfering with presynaptic release, uptake and postsynaptic actions of glutamate by mechanisms that are not well understood. Riluzole and related prodrugs with improved… read more here.
Keywords: efficacy glutamatergic; readily releasable; size readily; glutamatergic transmission ... See more keywords
Measuring the Readily Releasable Synaptic Vesicle Pool at the Drosophila Larval Neuromuscular Junction.
Sign Up to like & getrecommendations! Published in 2024 at "Cold Spring Harbor protocols"
DOI: 10.1101/pdb.prot108425
Abstract: Presynaptic homeostatic potentiation (PHP) is a type of homeostatic regulation that stabilizes synaptic output under conditions where postsynaptic receptor function is impaired. PHP manifests as a significant increase in presynaptic neurotransmitter release, compensating for decreased… read more here.
Keywords: calcium; readily releasable; neuromuscular junction; vesicle pool ... See more keywords