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Published in 2019 at "Human pathology"
DOI: 10.1016/j.humpath.2019.06.001
Abstract: LINE-1 (L1) retrotransposons are mobile genetic elements capable of "copy-and-pasting" their own sequences into random genomic loci and one of the proteins it uses to achieve mobility is LINE-1 open reading frame 1 protein (L1ORF1p).…
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Keywords:
frame protein;
reading frame;
l1orf1p expression;
expression ... See more keywords
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Published in 2017 at "Journal of theoretical biology"
DOI: 10.1016/j.jtbi.2017.09.019
Abstract: In this study we used non-overlapping parts of the two long open reading frames coding for nonstructural (NS) and capsid (VP) proteins of all available sequences of the Parvovirus B19 subgenotype 1a genome and found…
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Keywords:
transcription;
mutational pressure;
parvovirus b19;
reading frame ... See more keywords
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Published in 2020 at "Peptides"
DOI: 10.1016/j.peptides.2019.170192
Abstract: The novel peptide dwarf open reading frame (DWORF), highly conserved across species and expressed almost exclusively in cardiac ventricular muscle, may play a role in cardiac physiology and pathophysiology. The effect of direct administration of…
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Keywords:
rat hearts;
reading frame;
effects dworf;
dwarf open ... See more keywords
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1
Published in 2017 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btw820
Abstract: Abstract Summary Reading frame altering genomic variants can impact gene expression levels and the structure of protein products, thus potentially inducing disease phenotypes. Current annotation approaches report the impact of such variants in the context…
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Keywords:
reading frame;
frame;
stop lost;
cocos ... See more keywords
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3
Published in 2023 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.04888-22
Abstract: Recombination is one of the mechanisms that plays a crucial role in the genetic diversity and evolution of HAstV. We wished to investigate the emergence of HAstV recombinant strains and to analyze the whole-genome sequences…
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Keywords:
recombination;
reading frame;
recombinant strains;
human astrovirus ... See more keywords
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2
Published in 2022 at "RNA"
DOI: 10.1261/rna.079131.122
Abstract: A previous bioinformatic analysis predicted that the ysgA open reading frame of Bacillus subtilis encodes an RNA methyltransferase of the SPOUT superfamily. Here we show that YsgA is the 2'-O-methyltransferase that targets position G2553 (Escherichia…
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Keywords:
reading frame;
ysga;
23s rrna;
methyltransferase ... See more keywords
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Published in 2022 at "EMBO Reports"
DOI: 10.15252/embr.202154321
Abstract: Recent studies have identified numerous RNAs with both coding and noncoding functions. However, the sequence characteristics that determine this bifunctionality remain largely unknown. In the present study, we develop and test the open reading frame…
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Keywords:
coding noncoding;
orf dominance;
reading frame;
dominance ... See more keywords
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Published in 2022 at "Frontiers in Pediatrics"
DOI: 10.3389/fped.2022.985878
Abstract: Objective To explore the potential of walking alone milestone combined reading-frame rule to improve the early diagnosis of Duchenne muscular dystrophy (DMD). Method To retrospectively describe the genotype and phenotype of Duchenne and Becker muscular…
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Keywords:
reading;
reading frame;
walking alone;
frame rule ... See more keywords
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1
Published in 2023 at "Antioxidants"
DOI: 10.3390/antiox12020518
Abstract: Mitochondrial open reading frame of the 12S rRNA type-c (MOTS-c) is the most unearthed peptide encoded by mitochondrial DNA (mtDNA). It is an important regulator of the nuclear genome during times of stress because it…
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Keywords:
rrna type;
12s rrna;
frame 12s;
reading frame ... See more keywords
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Published in 2021 at "Biomedicines"
DOI: 10.3390/biomedicines9060618
Abstract: Upstream open reading frame (uORF)-mediated translational control has emerged as an important regulatory mechanism in human health and disease. However, a systematic search for cancer-associated somatic uORF mutations has not been performed. Here, we analyzed…
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Keywords:
termination codons;
reading frame;
upstream open;
cancer ... See more keywords