Methyltrimethoxysilane (MTM) as a Reagent for Direct Amidation of Carboxylic Acids.
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DOI: 10.1021/acs.orglett.1c04265
Abstract: Methyltrimethoxysilane [MTM, CH3Si(OMe)3] has been demonstrated to be an effective, inexpensive, and safe reagent for the direct amidation of carboxylic acids with amines. Two simple workup procedures that provide the pure amide product without the… read more here.
Keywords: reagent direct; direct amidation; carboxylic acids; amidation carboxylic ... See more keywords