Palladium Catalyzed Carbonylative Coupling of Alkyl Boron Reagents with Bromodifluoroacetamides
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DOI: 10.1021/acscatal.8b00420
Abstract: A catalytic protocol for the preparation of α,α-difluoro-β-alkyl-β-ketoamides is developed employing a Pd-mediated carbonylative Suzuki coupling between alkylboron reagents and bromodifluoroacetamides with COgen as the CO source. The reaction reveals good functional group tolerance providing… read more here.
Keywords: alkyl; carbonylative coupling; coupling alkyl; palladium catalyzed ... See more keywords