2H-Azirine-based Reagents for Chemoselective Bioconjugation at Carboxyl Residues inside Live Cells.
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DOI: 10.1021/jacs.9b12116
Abstract: Protein modification by chemical reagents has played an essential role in the treatment of human diseases. However, the reagents currently used are limited to the covalent modification of cysteine and lysine residues. It is thus… read more here.
Keywords: reagents chemoselective; azirine based; based reagents; carboxyl residues ... See more keywords